Results 71 to 80 of about 1,689,166 (267)

Natural sciences and chess: A romantic relationship missing from higher education curricula. [PDF]

Heliyon, 2023
Uskoković V.
europepmc   +1 more source

The nature of psychotherapy: natural science or human science?

, 1980
Bibliography: p. 152-161.
openaire   +2 more sources

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

IFN-γ licenses normal and pathogenic ALPK1/TIFA pathway in human monocytes

iScience
Summary: Alpha-kinase 1 (ALPK1) is an immune receptor sensing the bacterial nucleotide sugar ADP-heptose. ALPK1 phosphorylates TIFA leading to its oligomerization and downstream NF-κB activation.
Amandine Martin, Solène Caron, Mélissa Marcotte, Pauline Bronnec, Etienne Garneret, Nora Martel, Georgina Maalouf, Pascal Sève, David Saadoun, Yvan Jamilloux, Thomas Henry   +10 more
doaj   +1 more source

The natural selection of conservative science [PDF]

Studies in History and Philosophy of Science Part A, 2019
Social epistemologists have argued that high risk, high reward science has an important role to play in scientific communities. Recently, though, it has also been argued that various scientific fields seem to be trending towards conservatism -- the increasing production of what Kuhn (1970) would have called `normal science'.
openaire   +5 more sources

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Learning, economies of scale, and knowledge gap effects on power generation technology cost improvements

iScience
Summary: Cost reductions are essential for accelerating clean technology deployment. Because multiple factors influence costs, traditional one-factor learning models, solely relying on cumulative installed capacity as an explanatory variable, may ...
Yoga W. Pratama, Matthew J. Gidden, Jenna Greene, Andrew Zaiser, Gregory Nemet, Keywan Riahi   +5 more
doaj   +1 more source

Inferring the shape of data: a probabilistic framework for analysing experiments in the natural sciences. [PDF]

Proc Math Phys Eng Sci, 2022
Ray KK, Verma AR, Gonzalez RL, Kinz-Thompson CD.   +3 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Optical characteristics of laser medical instrument with side-firing fiber under complete bevel angle range

iScience
Summary: The side-firing instrument is studied under the complete bevel angle range. The fiber core and cladding are 0.6 mm and 0.66 mm, respectively, the fiber core refractive index is 1.457, and the fiber cladding refractive index is from 1.409 to 1 ...
Diqing Ying
doaj   +1 more source