Results 51 to 60 of about 2,055,109 (284)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Proceedings of the Davenport Academy of Natural Sciences [PDF]

, 1876
v.2 1876 ...
Davenport Academy of Natural Sciences.
core  

Dynamics of the oral microbiome during orthodontic treatment and antimicrobial advances for orthodontic appliances

iScience
Summary: The oral microbiome plays an important role in human health, and an imbalance of the oral microbiome could lead to oral and systemic diseases. Orthodontic treatment is an effective method to correct malocclusion.
Qin Niu, Si Chen, Rushui Bai, Yuntao Lu, Liying Peng, Bing Han, Tingting Yu   +6 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Blood mitochondrial metabolism predicts flight performance without lasting effects of early-life thyroid hormones

iScience
Summary: Early-life conditions can shape adult phenotypes by influencing processes linked to energetic homeostasis. Thyroid hormones (THs) enhance mitochondrial electron transport chain capacity (ETS) in fledglings, but whether this effect is permanent ...
Marlene Oefele, Michaela Hau, Suvi Ruuskanen, Stefania Casagrande   +3 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Positioning, navigation, and timing on the Moon and Mars with galactic cosmic rays

iScience
Summary: The muometric wireless navigation system (MuWNS) is a technology enabling signal reception for machine controlling and communication systems underground where a radio or GPS signal would normally be lost.
G. Leone, H.K.M. Tanaka, M. Holma, S. Krishnan, A.R. Duffy, T. Enqvist, P. Kuusiniemi, J. Joutsenvaara, G. Cerretto, E. Cantoni, M. Sellone, J. Marteau, D. Lo Presti, J.G. Szűcs, D. Varga   +14 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Commensal human gut microbes produce species specific neuroactive compounds

iScience
Summary: The gut microbiota communicates with multiple organs through neuroactive molecules, but the specific compounds produced remain unclear. We investigated eight commensal gut species, Lactococcus lactis, Enterococcus faecalis, Blautia producta ...
Anna M. Tingler, Charulekha Packirisamy, Alyssa Gutierrez, Adelaide E. Horvath, Makenna Grozis, Sigmund J. Haidacher, Kathleen M. Hoch, Anthony M. Haag, Numan Oezguen, Kristen A. Engevik, Amy C. Engevik, Thomas D. Horvath, Melinda A. Engevik   +12 more
doaj   +1 more source