Results 31 to 40 of about 1,689,166 (267)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Layer-by-layer coated probiotics with tannic acid-Ca2+ and casein phosphopeptide complexes for caries prevention and enamel remineralization

iScience
Summary: Dental caries is a common disease resulting from tooth demineralization caused by bacterial plaque. Probiotics have shown great potential against caries by regulating the balance of oral flora.
Ming-Xin Cao, Zhan-Yin Qian, Yan-Jie Liang, Qi-Yao Liu, Han-Ping Wang, Yang Meng, Yin-Song Wang, Yue Wang   +7 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Recent progress in Si/Ti3C2Tx MXene anode materials for lithium-ion batteries

iScience
Summary: Cardiovascular diseases (CVDs) are a major global health issue, causing significant morbidity and mortality worldwide. Early diagnosis and continuous monitoring of physiological signals are crucial for managing cardiovascular diseases ...
Xinyu Jiang, Chaoyang Tang, Xinchi Zhou, Jiwei Hou, Shan Jiang, Leichao Meng, Yi Zhang   +6 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Roles and therapeutic opportunities of ω-3 long-chain polyunsaturated fatty acids in lung cancer

iScience
Summary: Over the past decades, researchers have continuously investigated the potential functions of long-chain polyunsaturated fatty acids (LCPUFAs) in cancers, including lung cancer.
Jiang Luo, Shu Peng, Ziyu Jiang, Qingwei Wang, Mini Zhang, Yuxin Zeng, Yu Yuan, Min Xia, Zixi Hong, Yufei Yan, Yushuang Tan, Jiawen Tang, Conghua Xie, Yan Gong   +13 more
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Cutting-edge microneedle innovations: Transforming the landscape of cardiovascular and metabolic disease management

iScience
Summary: Cardiovascular diseases (CVDs) and metabolic disorders (MDs) have surfaced as formidable challenges to global health, significantly imperiling human well-being. Recently, microneedles (MNs) have garnered substantial interest within the realms of
Xiaoning Zhang, Ming Li, Qiang Gao, Xiaoya Kang, Jingyao Sun, Yao Huang, Hong Xu, Jing Xu, Songren Shu, Jian Zhuang, Yuan Huang   +10 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Computer-aided robotics for applications in fracture reduction surgery: Advances, challenges, and opportunities

iScience
Summary: The advancement of information technology and AI has boosted global economic and social development. Robot systems (RS) and computer-aided technology (CAT) are used in various domains, including social production and human existence. Traditional
Xianzheng Zhou, Yimiao Chen, Genyuan Miao, Yanchao Guo, Qinhe Zhang, Jianping Bi   +5 more
doaj   +1 more source