Results 41 to 50 of about 16,943,207 (295)

Dynamics of the oral microbiome during orthodontic treatment and antimicrobial advances for orthodontic appliances

iScience
Summary: The oral microbiome plays an important role in human health, and an imbalance of the oral microbiome could lead to oral and systemic diseases. Orthodontic treatment is an effective method to correct malocclusion.
Qin Niu, Si Chen, Rushui Bai, Yuntao Lu, Liying Peng, Bing Han, Tingting Yu   +6 more
doaj   +1 more source

Accretion around black holes: The geometry and spectra

iScience, 2022
Summary: Observations of black hole X-ray binaries and active galactic nuclei indicate that the accretion flows around black holes are composed of hot and cold gas, which have been theoretically described in terms of either a hot geometrically thick ...
B.F. Liu, Erlin Qiao
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Following the robot’s lead: Predicting human and robot movement from EEG in a motor learning HRI task

iScience
Summary: A large proportion of human behavior is organized in time in the form of sensorimotor sequences. Learning new behavioral sequences recruits cognitive functions with their neural underpinnings.
Tanaya Chatterjee, Adrien Guzzo, Alejandro Tlaie, Ahmad Kaddour, Charalambos Papaxanthis, Jeremie Gaveau, Peter Ford Dominey   +6 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Advances of 3D bioprinting technology for periodontal tissue regeneration

iScience
Summary: 3D bioprinting technology for periodontal tissue regeneration is an advanced manufacturing technique that utilizes three-dimensional (3D) printing principles to fabricate intricate, viable structures that are specifically devised to meet with ...
Huanhuan Chen, Yu Wang, Yue Lai, Chenda Meng, Xiner Ning, Tianmin Xu, Guangying Song, Yunfan Zhang, Yifan Lin, Bing Han   +9 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Layer-by-layer coated probiotics with tannic acid-Ca2+ and casein phosphopeptide complexes for caries prevention and enamel remineralization

iScience
Summary: Dental caries is a common disease resulting from tooth demineralization caused by bacterial plaque. Probiotics have shown great potential against caries by regulating the balance of oral flora.
Ming-Xin Cao, Zhan-Yin Qian, Yan-Jie Liang, Qi-Yao Liu, Han-Ping Wang, Yang Meng, Yin-Song Wang, Yue Wang   +7 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Recent progress in Si/Ti3C2Tx MXene anode materials for lithium-ion batteries

iScience
Summary: Cardiovascular diseases (CVDs) are a major global health issue, causing significant morbidity and mortality worldwide. Early diagnosis and continuous monitoring of physiological signals are crucial for managing cardiovascular diseases ...
Xinyu Jiang, Chaoyang Tang, Xinchi Zhou, Jiwei Hou, Shan Jiang, Leichao Meng, Yi Zhang   +6 more
doaj   +1 more source