Results 141 to 150 of about 5,415,293 (346)

Dynamics of interaction of natural science and technology in the history of the development of scientific and technical knowledge: philosophical and methodological analysis

, 2023
Vladimir I. Kurashov, Yaroslav V. Kurashov   +1 more
openalex   +2 more sources

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Natural Science [PDF]

The Elementary School Teacher and Course of Study, 1902
Wilbur S. Jackman, Ira B. Meyers
openaire   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Natural sciences at the service of art and cultural heritage: an interdisciplinary area in development and important challenges. [PDF]

Microb Biotechnol, 2021
Piñar G, Sterflinger K.
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Natural Sciences is debuting

Natural Sciences, 2021
Bretislav Friedrich, Marianne Bronner, Vivian Yam, Gerard Meijer   +3 more
doaj   +1 more source

Non-foundational criticality? On the need for a process ontology of the psychosocial [PDF]

, 2007
The articulation of critical dialects of psychology has typically involved a questioning of the foundational assumptions of the so-called mainstream. This has included critiques in the name of more adequate scientific foundations, but more recently these
Stenner, P.
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

A graphene-based photo-electro-thermal metamaterial for soft fixtures with superior grasping performance

iScience
Summary: Soft actuators are valued for their adaptability and diverse applications but often face challenges like slow response, high activation energy, and high energy consumption.
Bowen Yang, Xuanchen Dong, Wenhao Lv, Wenzhuo Liu, Mengying Lu, Zhe Liu, Tonghui Lu, Xianglin Li, Song Lv   +8 more
doaj   +1 more source