Increased Blood Levels of NfL, GFAP, and Placental Growth Factor After Radiotherapy to the Brain
ABSTRACT In this study, we analyzed biomarkers of neuronal, glial, and vascular injury in longitudinal paired samples of blood and cerebrospinal fluid after prophylactic cranial irradiation in patients with small cell lung cancer. Neurofilament light chain protein (NfL) and glial fibrillary acidic protein (GFAP) increased in serum and cerebrospinal ...
Erik Fernström +5 more
wiley +1 more source
The genetics and evolution of moth melanism in the absence of strong natural selection. [PDF]
Liu Y +10 more
europepmc +1 more source
Natural selection on mitochondrial DNA inParusand its relevance for phylogeographic studies
Robert M. Zink
openalex +1 more source
Transfer of individuals as a means of investigating natural selection in operation [PDF]
Olli Halkka +2 more
openalex +1 more source
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin +11 more
wiley +1 more source
Natural Selection in Transcription Factor-DNA Interaction Motifs: A Comparative and Population Genomics Perspective. [PDF]
Joshi M +3 more
europepmc +1 more source
Decoding triancestral origins, archaic introgression, and natural selection in the Japanese population by whole-genome sequencing [PDF]
Xiaoxi Liu +18 more
openalex +1 more source
Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller +6 more
wiley +1 more source
Evolution of GC-biased gene conversion by natural selection. [PDF]
Clessin A, Joseph J, Lartillot N.
europepmc +1 more source
Natural selection or genetic engineering: An emerging technologies librarian’s DNA [PDF]
Sarah-Jane Saravani, John Clayton
openalex

