Results 141 to 150 of about 14,815,342 (343)

Natural Selection, Irrationality and Monopolistic Competition [PDF]

open access: yes
This paper builds an evolutionary model of an industry where firms produce differentiated products. Firms have different average cost functions and different demand functions.
Luo, Guo Ying
core  

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Natural selection and birthweight

open access: yesAnnals of Human Biology, 1978
Mean birthweight, even before induced births became commonplace, is slightly lower than the birthweight at which perinatal mortality is lowest. This finding, once hard to explain by natural selection, is shown to be exactly in line with predictions from natural selection theory.
openaire   +2 more sources

Distinguishing Drift and Selection Empirically: “The Great Snail Debate” of the 1950s [PDF]

open access: yes, 2007
Biologists and philosophers have been extremely pessimistic about the possibility of demonstrating random drift in nature, particularly when it comes to distinguishing random drift from natural selection.
Millstein, Roberta L.
core  

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

Disease-specific HIV Nef identified in multiple patients with neurological disorders and cancers

open access: yesJournal of Virus Eradication, 2017
S. Lamers   +5 more
doaj   +1 more source

Is the evolutionary theory still useful?: A review with examples ¿Es todavía útil la teoría evolutiva?: Una revisión con ejemplos

open access: yesRevista Chilena de Historia Natural, 2010
Evolutionary biology is experiencing an exceptional process of revisión and outreach because of the 200-anniversary if the birth of Charles Darwin. As a consequence, the study of organic evolution and also its teaching are being discussed at several ...
ROBERTO F NESPOLO
doaj  

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