Results 181 to 190 of about 1,030,228 (245)
Knocking out genes to reveal drivers of natural selection on phenotypic traits: a study of the fitness consequences of albinism. [PDF]
Funk AT +5 more
europepmc +1 more source
Objectives Pulmonary fibrosis (PF) is a severe extra‐articular manifestation of rheumatoid arthritis (RA). The study aimed to externally validate a genetic risk score (GRS) and a combined risk score for predicting the risk of RA‐associated PF in an independent cohort of early‐RA patients. Methods This study utilized an inception cohort of 1118 patients
Mikael Brink +3 more
wiley +1 more source
Natural Selection Shaped Codon Usage Patterns in Wheat Dwarf Virus in Triticale. [PDF]
Wang J +7 more
europepmc +1 more source
Addressing Economic Insecurities Can Improve Patient‐Reported Outcomes in Lupus
Background Economic insecurities, such as food, housing, transportation, and financial challenges, are modifiable risk factors and influence patient‐reported outcomes (PROs) in systemic lupus erythematosus (SLE). We examined: 1) associations between economic insecurities and PROs; 2) the impact of screening and addressing economic insecurities during ...
Jay Patel +8 more
wiley +1 more source
Efficient Detection and Characterization of Targets of Natural Selection Using Transfer Learning. [PDF]
Arnab SP +3 more
europepmc +1 more source
This paper proposes two projector‐based Hopfield neural network (HNN) estimators for online, constrained parameter estimation under time‐varying data, additive disturbances, and slowly drifting physical parameters. The first is a constraint‐aware HNN that enforces linear equalities and inequalities (via slack neurons) and continuously tracks the ...
Miguel Pedro Silva
wiley +1 more source
Tracing human genetic histories and natural selection with precise local ancestry inference. [PDF]
Lerga-Jaso J +15 more
europepmc +1 more source
Natural selection and demography in ancient human introgression
Martin Petr
openalex +1 more source

