Results 71 to 80 of about 1,671,264 (305)

Financial analysis of managing bamboo stands in a natural forest [PDF]

open access: yes, 1993
This paper discusses the financial analysis of managing bamboo stands in natural forest. Throughout the analysis, actual costs incun-ed by the Forest Research Institute Malaysia (FRlM) in setting up trial plots in Kedah were studied.
Haron, Nor'ini, Mohamed, Azmy
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

How close to nature is close-to-nature pine silviculture?

open access: yesJournal of Forest Science, 2016
Structural parameters of Scots pine stands (129-191 years) on their natural sites (270-600 m a.s.l.) are described on 6 permanent research plots (PRP; 3 in managed stands using near-natural silvicultural practices and 3 in stands without active forest ...
L. Bílek   +6 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Genetic analysis of Latvian Salix alba L. and hybrid populations using nuclear and chloroplast DNA markers

open access: yesiForest - Biogeosciences and Forestry, 2017
Latvia is at the northern border of the species range of S. alba L. in Europe, and there has been some debate whether the Latvian populations of S. alba are autochthonous, as this species has long been planted in Latvia as an ornamental tree in gardens ...
Rungis D   +6 more
doaj   +1 more source

Optimal synchronization of Kuramoto oscillators: a dimensional reduction approach [PDF]

open access: yes, 2015
A recently proposed dimensional reduction approach for studying synchronization in the Kuramoto model is employed to build optimal network topologies to favor or to suppress synchronization.
Pinto, Rafael S., Saa, Alberto
core   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Spatially explicit structure of natural stands dominated by black spruce

open access: yesSilva Fennica, 2013
Black spruce [ (Mill.) BSP] regeneration emerges in clusters near the pre-existing boles within a few years after the passage of fire. This paper tested the hypothesis that black spruce forests still maintain the spatial structure deriving from postfire ...
Rossi, Sergio   +3 more
doaj   +1 more source

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