Results 121 to 130 of about 2,654,500 (350)
MIF as an oncogenic driver of low‐heterogeneity melanomas
Molecular Oncology, EarlyView.Shvefel and colleagues identified tumor‐secreted macrophage migration inhibitory factor (MIF) as an upregulated cytokine that mediates immune resistance in melanomas with low‐intratumoral heterogeneity. MIF and its functional paralogue D‐dopachrome tautomerase (D‐DT or MIF‐2) have overlapping but nonidentical signaling functions and are hypothesized to
Thuy T. Tran +4 more
wiley +1 more source
Diversity in Natural Transformation Frequencies and Regulation across
mBio, 2019 In Vibrio species, chitin-induced natural transformation enables bacteria to take up DNA from the external environment and integrate it into their genome.
Chelsea A. Simpson +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano +16 more
wiley +1 more source
A natural extension for the greedy beta-transformation with three deleted digits [PDF]
arXiv, 2008 We give an explicit expression for the invariant measure, absolutely continuous with respect to the Lebesgue measure, of the greedy beta-transformation with three deleted digits. We define a version of the natural extension of the transformation to obtain this expression. We get that the transformation is exact and weakly Bernoulli.
arxiv
Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding
FEBS Open Bio, EarlyView.The present work investigates the presence and the stability of miRNAs into RBCs, both native and engineered. The observed stability is due to the Ago2 bound resulting in minimal RISC. Indeed, if the miRNA‐Ago2 complex is present, miRNAs are protected from release or degradation and they are biologically active. Thus, RBCs can act as miRNA carriers for
Elena Perla +4 more
wiley +1 more source
Advanced Engineering Materials, EarlyView., 2023 The study presents the mechanical and in situ sensing performance of digital light processing‐enabled 2D lattice nanocomposites under monotonic tensile and repeated cyclic loading, and provides guidelines for the design of architectures suitable for strain sensors and smart lightweight structures.
Omar Waqas Saadi +3 more
wiley +1 more source
A remark on Yoneda's Lemma [PDF]
arXiv, 2017 Yoneda'e Lemma is about the canonical isomorphism of all the natural transformations from a given representable covariant (contravariant, reps.) functor (from a locally small category to the category of sets) to a covariant (contravariant, reps.) functor.
arxiv
Establishment and biological characterization of radioresistant colorectal cancer cell lines
FEBS Open Bio, EarlyView.Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu +10 more
wiley +1 more source
Similarity Transformations of the Lorentz Transformation [PDF]
arXiv, 2014 We supplement the Lorentz transform $L(v)$ with a new "Tunneling" transform $T(v)$. Application of this new transform to elementary quantum mechanics offers a novel, intuitive insight into the nature of quantum tunneling; in particular, the so called "Klein Paradox" is discussed.
arxiv