Results 161 to 170 of about 6,442,499 (284)

The Impact of Natural Transformation on the Acquisition of Antibiotic Resistance Determinants. [PDF]

mBio, 2022
Perez F, Stiefel U.
europepmc   +1 more source

Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi, Enrique Gonzalez Saez‐Diez, Joshua Rong, Beril Ay, Shabbir Merchant, Kathryn Yang, Darius Ebrahimi‐Fakhari   +6 more
wiley   +1 more source

High-resolution genomic analysis reveals abundant mosaic outcomes of bacterial natural transformation independent of MutS-mediated mismatch repair. [PDF]

mBio
Lombardino JM, Falbel TG, Dewey CN, Burton BM.   +3 more
europepmc   +1 more source

Markerless gene deletion in Ralstonia solanacearum based on its natural transformation competence. [PDF]

Front Microbiol, 2022
Yan J, Lin N, Wang X, Chen X, Wang H, Lin Q, Zhou X, Zhang L, Liao L.   +8 more
europepmc   +1 more source

Proceedings of the South London Entomological & Natural History Society

, 1897
1899 ...
South London Entomological and Natural History Society, South London Entomological and Natural History Society.   +1 more
core  

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Genomic and functional dissection of natural transformation-related genes in <i>Piscirickettsia salmonis</i>. [PDF]

Microbiol Spectr
Higuera-Llantén S, Ojeda N, Protz J, Marshall SH.   +3 more
europepmc   +1 more source

Biochemical Properties and Roles of DprA Protein in Bacterial Natural Transformation, Virulence, and Pilin Variation. [PDF]

J Bacteriol, 2023
Sharma DK, Misra HS, Bihani SC, Rajpurohit YS.   +3 more
europepmc   +1 more source

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin, Yue Andy Qi, Ying Hao, Catherine DeMarino, Samuel Darko, Irene Cortese, Daniel S. Reich, María I. Gaitán, Steven Jacobson, Bridgett J. Billioux, Bryan Smith, Avindra Nath   +11 more
wiley   +1 more source

Expanding natural transformation to improve beneficial lactic acid bacteria. [PDF]

FEMS Microbiol Rev, 2022
Di Giacomo S, Toussaint F, Ledesma-García L, Knoops A, Vande Capelle F, Fremaux C, Horvath P, Ladrière JM, Ait-Abderrahim H, Hols P, Mignolet J.   +10 more
europepmc   +1 more source