Results 71 to 80 of about 1,350,046 (300)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Amid overlapping global crises, many individuals experience psychological distress, anxiety, hopelessness, and a diminished sense of agency. Scholars increasingly argue that this erosion of perceived significance may be as consequential as climate ...
Christine Wamsler
doaj +1 more source
This text deals with the potential of Nature-Based Solutions as an important design action for teaching the sustainability of the built environment and heritage awareness. It provides an overview of relevant contents, methods, goals, teacher competencies, course types, and learning outcomes.
openaire +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Ecological significance of protected areas in the tropical mountains of Eastern Africa
Protected areas (PAs) are a tool and strategy for achieving multiple forest management objectives. This study employed ecological indicators to evaluate the effectiveness of PAs in tropical mountains of Eastern Africa.
Marco Andrew Njana
doaj +1 more source
Nature-Based Solutions and Climate Change – Four Shades of Green
'Nature-based -solutions' (NbS) aim to use nature in tackling challenges such as climate change, food security, water resources, or disaster risk management.
Sveriges lantbruksuniversitet. +2 more
core +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Publikacja finansowana ze środków funduszy norweskich oraz środków krajowych w ramach projektu „EkoMiasto. Kształcenie na rzecz zrównoważonego, inteligentnego i partycypacyjnego rozwoju miast” (FSS/2014/HEI/W/0081).
openaire +3 more sources
The Encyclopedia of Tourism Management and Marketing is, quite simply, the definitive reference work in the field. Carefully curated by leading tourism scholar Dimitrios Buhalis, this is the largest tourism management and marketing ontology that has ever been put together and offers a holistic examination of this interdisciplinary field.
Phelan, Anna, Ruhanen, L
openaire +3 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source

