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This dissertation is born out of the simple desire to understand what the German philosopher Friedrich Nietzsche (1844 – 1900) meant when he claimed throughout his corpus that humanity needs to be ‘naturalized’. I fulfill this through an examination of Nietzsche’s juvenilia, the notes leading to the publication of The Birth of Tragedy (1872) and a ...
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Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
Discrete Dynamics in Nature and Society
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Discrete Dynamics in Nature and Society
doaj +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Discrete Dynamics in Nature and Society
doaj +1 more source
Disaster risk reduction and Evangelical Christianity: a case for pluriversality in practice. [PDF]
Watson SD.
europepmc +1 more source
Golden Ratio as Universal Way of Knowledge and Reflection of Nature in Culture
Viktor Mykhalevych
openalex +2 more sources

