Results 31 to 40 of about 477,739 (260)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
People and NatureHow humans connect with nature impacts the well‐being of both people and ecosystems. Being disconnected from nature can lead to attitudes and behaviours that ultimately damage our physical and mental health and cause irreparable harm to the planet.
Xuanyi Wang, Shulin Chen
doaj +1 more source
Ecology and Evolution, 2021 The influence of environmental factors on the distribution and persistence of African elephants (Loxodonta africana) is pertinent to policy makers and managers to formulate balanced plans for different land‐use types.
Doubt Chibeya +5 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Australian Journal of Environmental EducationIn an era of accelerating ecological degradation, how might experimental art practices help audiences foster deeper, more empathetic engagement with the intelligence of living systems?
Keith Armstrong +5 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
On connecting natural rights with natural law
Persona y Derecho, 1970 Black, V. (Virginia) +1 more
openaire +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Connecting young people with greenspaces: The case for participatory video
People and Nature, 2023 The values that people hold are thought to be key in bringing about the transformative change needed to halt biodiversity loss. Caring for nature has been conceptualised as a relational value and is thought to be largely shaped in childhood and ...
Antonia Eastwood +3 more
doaj +1 more source