Results 111 to 120 of about 181,914,409 (290)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Socioscientific issues as a lens for examining the relationship between NOS understanding and argumentation skills

Disciplinary and Interdisciplinary Science Education Research
The present study investigated the relationship between undergraduate students’ views of nature of science (NOS) and their argumentation skills in the context of socioscientific issues (SSI). Using known frameworks, it investigated the link in three SSI:
Rola Khishfe
doaj   +1 more source

The credibility crisis and democratic governance: how to reform university governance to be compatible with the nature of science. [PDF]

R Soc Open Sci, 2023
Dienes Z.
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Living the DReaM: The interrelations between statistical, scientific and nature of science uncertainty articulations through citizen science. [PDF]

Instr Sci, 2023
Aridor K, Dvir M, Tsybulsky D, Ben-Zvi D.   +3 more
europepmc   +1 more source

Information Management Policy - King Abdullah University of Science and Technology

, 2011
Records, Information and Archies Management Policy of King Abdullah University of Science and TechnologyRecords, Information and Archives Management Policy of King Abdullah University of Science and ...
King Abdullah University of Science and Technology
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Investigation of Pre-service Teachers' Conceptions of the Nature of Science Based on the LDA Model. [PDF]

Sci Educ (Dordr), 2023
Wang M, Gao S, Gui W, Ye J, Mi S.
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

A Systematic Review of Research on Family Resemblance Approach to Nature of Science in Science Education. [PDF]

Sci Educ (Dordr), 2022
Cheung KKC, Erduran S.
europepmc   +1 more source