Results 131 to 140 of about 181,914,409 (290)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Exploring Ethiopian Secondary School Science Teachers’ Conceptions about the Nature of Scientific Knowledge (NOSK)

open access: yesEducation Sciences
This study examined secondary school science teachers’ conceptions of the nature of scientific knowledge (NOSK). The participants were convenient samples consisting of 48 (M = 38, F = 10) teachers from three secondary schools. An open-ended questionnaire
Tadele Demelash Teshale   +2 more
doaj   +1 more source

Representations of nature of science in school science textbooks

open access: yes, 2017
The development of informed nature of science (NOS) views is considered an integral component of scientific literacy, and a central focus of the majority of national science education reform documents worldwide (e.g., American Association for the ...
McDonald, Christine   +1 more
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

SCIENCE AND RELIGION IN THE KRAKÓW SCHOOL

open access: yesZygon, 2015
This article outlines the contributions of the Kraków School to the field of science and religion. The Kraków School is a group of philosophers, scientists, and theologians who belong to the milieu of the Copernicus Center for Interdisciplinary Studies.
doaj   +2 more sources

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

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