Results 61 to 70 of about 493,608 (306)

Chemotherapy-induced nausea and vomiting: exploring patients’ subjective experience

, 2016
Background: This study aimed to explore the subjective experience of nausea and vomiting during chemotherapy treatment among breast cancer patients and the impacts on their daily lives.
Zakaria, Noor Salihah, Lua, Pei Lin, Mamat, Nik Mazlan   +2 more
core   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Tryptophan depletion increases nausea, headache and photophobia in migraine sufferers [PDF]

, 2006
Sensitivity to light was investigated 5 and 8 h after consumption of an amino acid drink which contained L-tryptophan (balanced amino acid condition: 19 controls and 22 migraine sufferers) or which produced a short-term reduction in brain serotonin ...
Drummond, P.D.
core  

Neurological, Neurodevelopmental and Treatment Outcomes in Patients With Pyruvate Dehydrogenase Complex Deficiency

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of this study was to characterize intellectual and motor function, neurological features including epilepsy, treatment response, and adaptive behavior in patients with pyruvate dehydrogenase complex deficiency (PDCD) in Sweden.
Antri Savvidou, Colin Reilly, Kalliopi Sofou, Sofia Ygberg, Erik A. Eklund, Karin Naess, Niklas Darin   +6 more
wiley   +1 more source

Nurses' comfort care of transarterial chemoembolization patients based on their perceptions around postembolization syndrome and symptom interference

Nursing Open, 2023
Aim Post‐embolization syndrome is a common adverse event following trans‐arterial chemoembolization, which negatively impacts the daily life of the patients involved.
Myoung Soo Kim, Minkyeong Kang, Jiwon Park, Jung Mi Ryu   +3 more
doaj   +1 more source

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source

Comparison of the effects of self-selected music and prefixed music on preoperative anxiety in adults undergoing laparoscopic surgery

The Indian Anaesthetists' Forum
Background and Aims: Preoperative anxiety can complicate patient outcomes. Music is a noninvasive method to allay anxiety, as revealed in studies. Self-selected (SS) versus prefixed (PF) music had not been studied much.
K. V Meghana, Pratiti Choudhuri, Amita Gupta, Anju Gupta   +3 more
doaj   +1 more source

Migraine and School Performance in Preadolescent Children

Pediatric Neurology Briefs, 2012
Researchers at the Glia Institute, Brazil; Albert Einstein College of Medicine, NY; and other centers conducted a population-based study of school performance in children in Brazil with migraine.
J Gordon Millichap
doaj   +1 more source

Does acupressure help reduce nausea and vomiting in palliative care patients? A double blind randomised controlled trial [PDF]

, 2020
Introduction: Nausea and vomiting are common symptoms for patients with advanced cancer. While there is evidence for acupuncture point stimulation for treatment of these symptoms for patients having anticancer treatment, there is little for when they are
Blaken, Alison, Perkins, Paul, Parker, Rebecca, Akyea, Ralph K., Parkinson, Anne   +4 more
core   +1 more source

Charting Morphotoxicity With Complementary Embryo Models

Advanced Healthcare Materials, EarlyView.
Three human embryo models of the peri‐implantation stages are exposed to a library of compounds. The (toxic) effects of the compounds are analyzed through automated image analysis pipelines. By evaluating the differential responses of the embryo models, this study underscores the importance of testing complementary embryo models to achieve robust and ...
Dorian G. Luijkx, Pauline L. Balder, Romy M. L. Verhagen, Vinidhra Shankar, Barry Jutten, Pinak Samal, Timo Rademakers, Clemens A. van Blitterswijk, Stefan Giselbrecht, Erik J. Vrij   +9 more
wiley   +1 more source