Medicine ScienceSubstance P (SP) is a peptide neurotransmitter that plays a role in pain transmission, stress, inflammation, and emesis through neurokinin-1 receptor (NK-1R).
Selma Cirrik +3 more
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Oral Drug Delivery Systems Based on Ordered Mesoporous Silica Nanoparticles for Modulating the Release of Aprepitant [PDF]
, 2021 Theodora Christoforidou +8 more
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Indian Journal of AnaesthesiaBackground and Aims: Postoperative nausea and vomiting (PONV) is a common complication after surgery. Preventing PONV in high-risk patients often requires a multimodal approach combining antiemetic drugs with diverse mechanisms.
Madhusudan P. Singh +3 more
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Acta Dermato-Venereologica, 2019 The aim of this multicentre, randomized, double-blind, placebo-controlled, cross-over, phase-II study was to determine the antipruritic effect of aprepitant vs.
Athanasios Tsianakas +12 more
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Two Cases of Fatal Encephalopathy Related to Ifosfamide: An Adverse Role of Aprepitant
Case Reports in Oncology, 2014 Ifosfamide is used in the treatment of sarcomas and other tumors. It sometimes provokes encephalopathy, which is a serious complication even if it is usually reversible within 48-72 h after drug cessation.
Alice Séjourné +6 more
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Cytotoxic and apoptotic effects of neurokinin-1 receptor (NK1R) antagonist on multiple myeloma cells [PDF]
مجله علمی دانشگاه علوم پزشکی کردستان, 2019 Background and Aim: Despite therapeutic improvements in recent decades, multiple myeloma (MM) still remains as one of the leading causes of death all over the world. Previous studies have indicated role of neurokinin-1 receptor (NK1R) in the pathogenesis
Elham Razani, Davood Bashash
doaj +1 more source
A Comparison of the Efficacy of 5 mg Olanzapine and Aprepitant in the Prevention of Multiple‐Day Cisplatin Chemotherapy‐Induced Nausea and Vomiting [PDF]
, 2022 Guang Liu +14 more
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Virtual screening reveals aprepitant to be a potent inhibitor of neutral sphingomyelinase 2: implications in blockade of exosome release in cancer therapy [PDF]
, 2023 Milad Moloudizargari +5 more
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Treatment for Refractory Pruritus Using Oral Aprepitant [PDF]
, 2016 Joon Huh +4 more
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Efficacy of single dose NEPA, a fixed combination of netupitant and palonosetron, versus a 3-day regimen of aprepitant/granisetron (APR/GRAN) for prevention of nausea in patients receiving high dose cisplatin [PDF]
, 2018 Arunee Dechaphunkul +3 more
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