Results 21 to 30 of about 8,463 (257)
Anti-Cancer Effect of Aprepitant on Nb4 Leukemic Cells
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2017 BACKGROUND AND OBJECTIVE: Genetic studies have demonstrated that the neurokini-1 Receptor (NK1R (is frequently involved in the pathogenesis of wide assortment of human malignancies, including acute promyelocytic leukemia (APL).
E Razani +4 more
doaj +1 more source
Drug Design, Development and Therapy, 2020 Xiao-nan Zhao,* Zhen-zi Bai,* Cheng-hua Li, Chuan-lun Sheng, Hong-yan Li Department of Infectious, The Third Hospital of Jilin University, Changchun City, Jilin Province 130033, People’s Republic of China*These authors contributed equally to this ...
Zhao X, Bai Z, Li C, Sheng C, Li H
doaj +1 more source
Prediction of Moderate to Severe Delayed Chemotherapy-Induced Nausea Using a Novel Algorithm Incorporating Individual Patient Factors. [PDF]
Cancer MedABSTRACT Purpose Chemotherapy‐induced vomiting and nausea (CINV) is difficult to accurately predict, especially in the delayed phase and can negatively affect a patient's' quality of life as well as reduce their motivation to continue lifesaving therapy.
Maity AP +9 more
europepmc +2 more sources
Aprepitant inhibits the development and metastasis of gallbladder cancer via ROS and MAPK activation
BMC Cancer, 2023 Background Aprepitant, as a neurokinin-1 receptor (NK-1R) antagonist, originally applied for curing chemotherapy-induced nausea and vomiting, has been reported to have significant antitumor effect on several malignant tumors.
Xueyan Cao +9 more
doaj +1 more source
The use of aprepitant in the first cycle of moderately emetogenic chemotherapy in patients with colorectal cancer: its preventive effect on chemotherapy-induced nausea and vomiting [PDF]
Korean Journal of Clinical Oncology, 2013 Purpose: There have been fever studies about the effectiveness of aprepitant in the first cycle of moderately emetogenic chemotherapy. The aim of this study was to determine whether aprepitant shows the effectiveness for prevention of chemotherapy ...
Jung Won Ryu +4 more
doaj +1 more source
Targeting tachykinin receptors in neuroblastoma [PDF]
, 2016 Neuroblastoma is the most common extracranial tumor in children. Despite aggressive multimodal treatment, high-risk neuroblastoma remains a clinical challenge with survival rates below 50%.
Althoff, Kristina +14 more
core +7 more sources
Frontiers in Public Health, 2021 Objectives: The aim of this systematic review is to assess the published cost-effectiveness analyses of aprepitant for patients with chemotherapy-induced nausea and vomiting (CINV).Methods: A systematic literature search was performed on PubMed, EMbase ...
Tingting Qiu +6 more
doaj +1 more source
Pharmaceutics, 2020 This study aimed to improve the solubility and dissolution of aprepitant, a drug with poor aqueous solubility, using a phosphatidylcholine (PC)-based solid dispersion system.
Sooho Yeo +4 more
doaj +1 more source
Influence of aprepitant on the pharmacodynamics and pharmacokinetics of gliclazide in rats and rabbits [PDF]
PeerJ, 2018 Background Concomitant drug administration is a general phenomenon in patients with chronic diseases such as diabetes mellitus. Among the currently available oral antidiabetic drugs, gliclazide is a commonly prescribed drug considering its multiple ...
Raghunandan Reddy Kura +2 more
doaj +2 more sources
CAQ Corner: Basic concepts of transplant immunology
, 2022 Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source