Results 121 to 130 of about 319,797 (300)

Physiologically Based Pharmacokinetic Modeling to Assess Transporter‐Mediated Drug–Drug Interactions in Support of Labeling Recommendations for Zavegepant Nasal Spray

Clinical Pharmacology &Therapeutics, EarlyView.
Zavegepant nasal spray, a calcitonin gene‐related peptide receptor antagonist indicated for acute treatment of migraine with or without aura in adults, is a substrate for organic anion transporting polypeptide 1B3 (OATP1B3), Na+/taurocholate cotransporting polypeptide (NTCP), P‐glycoprotein (P‐gp), and cytochrome P450 3A4 (CYP3A4).
Alice Ke, Ernesto Callegari, Manthena V.S. Varma, Mayur K Ladumor, Chieko Muto, Richard J. Bertz, Hannah M. Jones, Vaishali Sahasrabudhe, Jing Liu   +8 more
wiley   +1 more source

Serum Thyroid Hormone level in women with Nausea and Vomiting in Early Pregnancy

Medical Laboratory Journal, 2008
Background and Objectives: The hyperthyroidism, caused in Pregnancy, may Leads to nausea and vomiting. The aim of this study was to establish the relationship between the serum thyroid stimulating hormone (TSH) and thyroxin.
AR Mansourian, f Shahmohammdi, HR Mansourian   +2 more
doaj  

Toward Fit‐for‐Purpose Data for Drug Assessment in Non‐small Cell Lung Cancer: A Core Dataset

Clinical Pharmacology &Therapeutics, EarlyView.
Considering the high unmet medical need in people with non‐small cell lung cancer (NSCLC), the drug assessment for targeted therapies often rely on small populations and single‐arm trials, challenging the evaluation by regulatory authorities, health technology assessment bodies (HTAb), and clinicians.
Geeske F. Grit, Maaike van Dartel, Laura Rodwell, Hanneke van der Woude, Cornelis Boersma, Peter G. M. Mol, Doranne Hilarius   +6 more
wiley   +1 more source

Nausea and vomiting

, 2015
Nausea and vomiting are symptoms commonly experienced in advanced disease, especially the cancer population. Clear understanding of the different concepts surrounding nausea and vomiting is essential and will aid in screening, preventing, assessing, and ...
Kimberly Chow, Daniel Cogan, Sonni Mun
core   +1 more source

Photo Quiz: Globose Yeast‐Like Forms With Multiple Peripheral Buds in Urine and Cervical Cytology

Diagnostic Cytopathology, EarlyView.
ABSTRACT A 26‐year‐old immunocompetent woman with a history of noninvasive, low‐grade papillary urothelial carcinoma presented with persistent upper abdominal pain. Urine cytology, performed for bladder tumor surveillance, revealed globose, yeast‐like forms (10–30 μm) with thick walls and multiple narrowly attached peripheral buds in a “ship wheel ...
Adil Menon, Rachel Koch, Caroline Abramovich   +2 more
wiley   +1 more source

Interventional therapies for chronic heart failure: An overview of recent developments

ESC Heart Failure, Volume 12, Issue 2, Page 1081-1094, April 2025.
Abstract Heart failure (HF), the final manifestation of most cardiovascular diseases, has become a major global health concern, affecting millions of individuals. Despite basic drug treatments, patients present with high morbidity and mortality rates. However, recent advancements in interventional therapy have shown promising results in improving the ...
Bingchen Guo, Si Shi, Yutong Guo, Jie Xiong, Bo Wang, Zengxiang Dong, Dianyu Gao, Yingfeng Tu   +7 more
wiley   +1 more source

Gastric Myoelectrical Activity Patterns and Water‐Load Satiety Test in Patients With Chronic Dyspeptic Symptoms

JGH Open
Background/Aims Patients with chronic dyspeptic symptoms may or may not experience nausea and vomiting. Consensus papers suggested that gastroparesis should be defined by symptoms like nausea and vomiting rather than investigations only. Recognizing that
Uday C. Ghoshal, Mahesh K. Goenka, Uzma Mustafa, Awanish Tewari, Nikhil Sonthalia, Subhamoy Das, Nabaruna Chakraborty, Akash Roy, Shruti Keyal, Sourish Roy   +9 more
doaj   +1 more source

Self-management of cancer treatment-related fatigue, nausea, vomiting and oral mucositis in Chinese cancer patients [PDF]

, 2011
Background: Treatment-related symptoms continue to place a significant burden on many cancer patients. Many side effects require patients to engage in a range of self-management actions.
Lou, Yan
core  

Exploring the efficacy and safety of perampanel in epilepsia partialis continua: A case series

Epileptic Disorders, EarlyView.
Abstract Background Epilepsia partialis continua (EPC) is a form of focal motor status epilepticus (SE), which is commonly drug‐resistant requiring treatment with multiple antiseizure medications (ASM). There are no established guidelines for pharmacological management.
Setareh Lahsaee, Kristin M. Ikeda, Stephanie Woodroffe, Benjamin P. Whatley   +3 more
wiley   +1 more source

Evaluation of risk factors predicting chemotherapy-related nausea and vomiting : results from a european prospective observational study

, 2014
Context Demographic, personal, clinical, and behavioral factors predicting chemotherapy-induced nausea and vomiting (CINV) have been assessed in the past, but inconsistencies exist in the literature, studies have methodological shortcomings, and many ...
Gu, A, Novoa, S. A., Gu, A., Molasiotis, A., Isambert, N, Aapro, M., Gascon, P, Isambert, N., Aapro, M, Roila, F, Roila, F., Gascon, P., Molassiotis, A, Burke, TA, Dicato, M., Dicato, M, Novoa, SA, Burke, T. A.   +17 more
core   +1 more source