Results 171 to 180 of about 321,570 (302)

Tofacitinib Regulates β‐Catenin Nuclear Translocation to Inhibit FLS Migration and Alleviate Clinical Symptoms of RA

iNew Medicine, EarlyView.
ABSTRACT Objective Tofacitinib is a Janus kinase (JAK) inhibitor approved for the treatment of moderate‐to‐severe rheumatoid arthritis (RA). However, its synovium‐related molecular mechanisms, particularly its regulatory effect on fibroblast‐like synoviocyte (FLS) migration, remain incompletely understood.
Shuqi Fang, Tianjing Zhang, Ling Hu, Ruijin Liu, Leyi Jia, Menglin Bai, Jiale Dong, Yuchen Zhao, Han Wang, Lei Zhang, Tao Li, Youcai Deng, Xianzheng Zhang, Lingling Zhang   +13 more
wiley   +1 more source

Vitamin B6 in nausea and vomiting of pregnancy: metabolism, mechanisms, and clinical implications-a narrative review. [PDF]

Front Nutr
Gao Z, Yao Y, Chang H, Wang Y, Yu J, Shi B, Gao Y, Wu X, Gao J.   +8 more
europepmc   +1 more source

Chlorfenapyr Induces Hepatotoxicity Associated With Oxidative Stress and Mitochondrial Dysfunction Involving Keap1/Nrf2 Signaling

Journal of Applied Toxicology, EarlyView.
ABSTRACT Chlorfenapyr (CHL) is a widely used pyrrole insecticide, but its hepatotoxic effects and underlying mechanisms remain incompletely understood. This study investigated the toxic effects of CHL on rat liver and BRL‐3A hepatocytes and explored the involvement of the Keap1/Nrf2 signaling pathway. Rats were administered CHL (10, 20, or 30 mg/kg) by
Dongquan Zhao, Jia Li, Cheng Li, Hua He, Lipu Deng   +4 more
wiley   +1 more source

Global inequitable distribution of seminal studies of chemotherapy-induced nausea and vomiting. [PDF]

Support Care Cancer
Chai GW, Tan Y, Leigh J, Watanabe D, Iihara H, Chow R.   +5 more
europepmc   +1 more source

Validation of Virtual Reality Simulations for Anatomical Landmarks in Panoramic Radiographs

Journal of Dental Education, EarlyView.
ABSTRACT Objective This study assessed the validity of panoramic anatomical virtual reality (VR) software among senior dental students. Materials and Methods A total of 79 fourth‐year dental students were randomly divided into two groups in this crossover study. Students’ knowledge of panoramic anatomical landmarks was tested.
Daniah M. Alhazmi, Sarah Alnamlah, Noura Alsufyani, Asma'a Faden, Fatima M. Jadu   +4 more
wiley   +1 more source

Elderly male with nausea and vomiting

Journal of the American College of Emergency Physicians Open, 2023
Gayle M. Galletta
doaj   +1 more source

Management of nausea and vomiting with claudin 18.2-targeted therapy in upper gastrointestinal cancer. [PDF]

ESMO Gastrointest Oncol
Wu Z, Shitara K, Lorenzen S.
europepmc   +1 more source

When Nausea and Vomiting Are Something Else Entirely, It's Not Gastroparesis: A Report of Two Cases. [PDF]

Cureus
Shaw R, Allen K, Thelin C, Klam RH, Sujka JA.   +4 more
europepmc   +1 more source

Pharmacokinetics and Pharmacodynamics of a Single Oral Dose of Ascelia‐Manganese‐Based MRI Contrast Agent (ACE‐MBCA) in Adult Subjects With and Without Hepatic Impairment

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Orally administered Ascelia‐manganese‐based contrast agent (ACE‐MBCA) is used for liver MRI, but its feasibility in patients with hepatic dysfunction remains unknown. Purpose To investigate the pharmacokinetics (PK), pharmacodynamics, and safety of ACE‐MBCA in subjects without/with hepatic impairment.
Amit G. Singal, Eric Lawitz, Andreas Norlin, Nadilka Hettiarachchige, Thomas Bengtsson, Bachir Taouli   +5 more
wiley   +1 more source

Physiology of Nausea and Vomiting

British Journal of Anaesthesia, 1992
openaire   +2 more sources