Results 61 to 70 of about 327,545 (257)

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden   +3 more
wiley   +1 more source

Efficacy of metoclopramide and dexamethasone for postoperative nausea and vomiting: a double-blind clinical trial [PDF]

open access: yes
Postoperative nausea and vomiting are common complications of anaesthesia. This double-blind clinical trial assessed the incidence of nausea and vomiting after cataract surgery with intravenous anaesthesia in 100 patients randomly assigned to ...
عیسی زاده فر, خاطره   +3 more
core   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad   +4 more
wiley   +1 more source

Economic evaluation of ondansetron: Preliminary analysis using clinical trial data prior to price setting [PDF]

open access: yes, 1992
This article has been made available through the Brunel Open Access Publishing Fund and is available from the specified link - Copyright © 1992 Macmillan Press Ltd.This study combines secondary analysis of efficacy and side-effect data from a randomised ...
Buxton, MJ, O'Brien, BJ
core   +4 more sources

POSTOPERATIVE NAUSEA AND VOMITING

open access: yes, 2002
The vomiting reflex evolved as a defensive one centered mainly on the gastrointestinal tract. It is also a symptom of many diseases of the gastrointestinal tract and other systems.
Yusufu, LMD
core   +2 more sources

EFFECT OF IV DEXAMETHASONE ON INCIDENCE OF NAUSEA AND VOMITING AND BEGINNING OF ORAL INTAKE IN ADENOTONSILLECTOMY

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2006
BACKGROUND & OBJECTIVE: Tonsillectomy and adenotonsillectomy are two of the most common surgical procedures performed in children. Although new surgical technique has reduced immediate postoperative hemorrhage, other complications such as postoperative ...
A A. Etemadi Aleagha,   +3 more
doaj  

Maternity Nurses' Knowledge and Practice Regarding Postoperative Nausea and Vomiting Risk Screening [PDF]

open access: yesEgyptian Journal of Health Care
Background: Postoperative nausea and vomiting (PONV) is any nausea or vomiting within the first 24 hours after surgery that may lead to many physical and psychological complications.
Yaman Ibrahim Soliman   +3 more
doaj   +1 more source

Baseline nausea and vomiting severity.

open access: yes, 2017
Baseline nausea and vomiting severity.
Navindra Persaud (507180)   +1 more
core   +1 more source

Acute toxicity of ADB‐CHMINACA ‐ a case series of patients with pronounced central nervous symptoms including the posterior reversible encephalopathic syndrome

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen   +7 more
wiley   +1 more source

Evaluation of risk factors predicting chemotherapy-related nausea and vomiting : results from a european prospective observational study

open access: yes, 2014
Context Demographic, personal, clinical, and behavioral factors predicting chemotherapy-induced nausea and vomiting (CINV) have been assessed in the past, but inconsistencies exist in the literature, studies have methodological shortcomings, and many ...
Gu, A   +17 more
core   +1 more source

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