Results 51 to 60 of about 319,797 (300)

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Escitalopram for Psychogenic Nausea and Vomiting: A Report of Two Cases

Journal of the Formosan Medical Association, 2011
Psychogenic nausea and vomiting is defined as vomiting without any obvious organic pathology or vomiting with a psychological etiology. The treatment for such a condition is a challenge in clinical practice.
Wen-Yu Hsu, Si-Sheng Huang, Nan-Ying Chiu   +2 more
doaj   +1 more source

Bio‐Inspired Biopolymeric Implantable Platform for Localized and Sustained Drug Delivery in Solid Tumor Treatment

Advanced Functional Materials, EarlyView.
A bio‐inspired biopolymeric implantable drug delivery platform enables localized and sustained release of 7‐ethyl‐10‐hydroxycamptothecin (SN‐38) in solid tumor treatment. The three‐dimensional (3D) structured crosslinked‐chitosan implants are fabricated via 3D‐printed molds and provide drug release over 3 months, significantly inhibiting tumor growth ...
Mercedes Lozano‐Garcia, Constantine Vogiatzis, Alejandra Planells‐Devesa, Emre Dikici, Caroline Vieira Maluf, Vasudev Vivekanand Nayak, Paulo G. Coelho, Lukasz Witek, Alicia Bilbao, Daniel Bilbao, Prasoon Mohan, Sapna Deo, Sylvia Daunert   +12 more
wiley   +1 more source

Unusual cause of nausea and vomiting [PDF]

Journal of Clinical and Scientific Research, 2016
Adrenal insufficiency can manifest with various symptoms ranging from haemodynamic compromise to non-specific symptoms like myalgia, anorexia, and loss of weight. Aetiology can be primary adrenal disorder or secondary to suppression of HPA axis.
Nandakrishna B, Muralidhar V, Vidyasagar S   +2 more
doaj   +1 more source

Does acupressure help reduce nausea and vomiting in palliative care patients? A double blind randomised controlled trial [PDF]

, 2020
Introduction: Nausea and vomiting are common symptoms for patients with advanced cancer. While there is evidence for acupuncture point stimulation for treatment of these symptoms for patients having anticancer treatment, there is little for when they are
Blaken, Alison, Perkins, Paul, Parker, Rebecca, Akyea, Ralph K., Parkinson, Anne   +4 more
core   +1 more source

Inhalable ROS‐Responsive Nanospray Activates PPAR‐γ to Restore Macrophage Mitochondrial Homeostasis and Attenuate Radiation‐Induced Lung Injury

Advanced Science, EarlyView.
A nebulized nanoassembly alleviates radiation‐induced lung injury by reprogramming macrophages through coordinated ROS scavenging, NAD+ replenishment, and PPAR‐γ activation. Redox balance, mitochondrial homeostasis, and immune regulation are restored, revealing a microenvironment‐centered strategy for localized radioprotection.
Mingquan Gao, Xudong Yu, Ziqian Shang, Mengyao Tan, Xie Huang, Zaizhi Du, Xiaojiao Wang, Xinrui Yang, Ximei Luo, Weidong Wang, Rong Li, Shenglin Luo   +11 more
wiley   +1 more source

Prophylactic Effect of Dexamethasone on Postoperative Nausea and Vomiting in Patients Undergoing Tympanomastoid Surgery [PDF]

Journal of Kerman University of Medical Sciences, 2003
Postoperative nausea and vomiting is an unpleasant, distressing, and exhausting experience for patient. This is more common and severe in tympanomastoid surgery. The role of dexamethasone prevention of this complication is unclear and during recent years
J Saied, S.M.R Ahmadi-Moosavi, H Eslami
doaj  

Effect of Inhaled Peppermint Aromatherapy on Chemotherapy-Induced Acute Nausea and Vomiting among Women with Breast Cancer in Gresik Regency

Indonesian Journal of Cancer, 2023
Background: Chemotherapy-induced acute nausea and vomiting are commonly experienced by breast cancer patients. Therefore, this study aimed to determine the effect of inhaled peppermint aromatherapy on chemotherapy-induced acute nausea and vomiting among ...
Istiroha Istiroha, Roihatul Zahroh, Qonitatin Wafiyah, Yuanita Syaiful   +3 more
doaj   +1 more source

Heavy Metal Contamination: Impacts From Plants to the Food Chain and Eco‐Friendly Amelioration Strategies

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Heavy metal pollution reduces soil health and threatens food safety by entering plants; however, the use of nanoparticles, biofertilizers, and organic fertilizers such as biochar offers a promising strategy for improvement and sustainable agriculture. ABSTRACT Heavy metal (HM) pollution, resulting from human activities such as mining and the excessive ...
Sina Siavash Moghaddam, Latifeh Pourakbar, Sevda Alizadeh, Zahra Alizadeh, Jelena Popović‐Djordjević   +4 more
wiley   +1 more source

EFFECT OF COUNSELLING ON FREQUENCY AND SEVERITY OF NAUSEA AND VOMITING IN PREGNANCY (NVP)

Indonesian Midwifery and Health Sciences Journal, 2021
Background: Nausea and vomiting are commonly during early pregnancy. Nausea and vomiting significantly decrease in quality of life. Objective:This study aimed to explain the effect of counseling on the frequency and level of nausea and vomiting in ...
Luh Sukeningsih, Baksono Winardi, Tiyas Kusumaningrum   +2 more
doaj   +1 more source