Results 181 to 190 of about 9,275 (242)

Centrally Acting Skeletal Muscle Relaxants Sharing Molecular Targets with Drugs for Neuropathic Pain Management. [PDF]

Brain Sci
Kirchlechner-Farkas JM, Karadi DA, Boldizsár I, Essmat N, Galambos AR, Lincmajer ZP, Abbood SK, Király K, Szökő É, Tábi T, Al-Khrasani M.   +10 more
europepmc   +1 more source

Modification of Closed-State Inactivation in Voltage-Gated Sodium Channel Na_v1.7 by Two Novel Arachnid Toxins. [PDF]

Toxins (Basel)
Johnson JW, Rikli HG, Johnson SR.
europepmc   +1 more source

Disulfide-constrained Fabs overcome target size limitation for high-resolution single particle cryoEM. [PDF]

Nat Commun
Kung JE, Johnson MC, Tegunov D, Jao CC, Wu P, Oh A, Lin M, Daria JM, Koth CM, Arthur CP, Rohou A, Sudhamsu J.   +11 more
europepmc   +1 more source

Cannabidiol combined with GABAergic drugs but not with sodium channel blockers prevents the development of drug-resistance seizures in a preclinical model. [PDF]

Front Pharmacol
Fuentes-Mejia M, Fallico MJ, Talevi A, Gavernet L, Orozco-Suárez SA, Rocha L.   +5 more
europepmc   +1 more source

Three-dimensional Quantitative Structure-activity Relationship, Molecular Docking and Absorption, Distribution, Metabolism, and Excretion Studies of Lidocaine Analogs Pertaining to Voltage-gated Sodium Channel Na_v1.7 Inhibition for the Management of Neuropathic Pain. [PDF]

Int J Appl Basic Med Res
Sharma S, Rana P, Dhingra N, Kaur T.
europepmc   +1 more source

Enhanced trafficking of an inherited erythromelalgia Na_V1.7 mutant channel at a physiological temperature. [PDF]

Neurobiol Pain
Mis MA, Tyagi S, Akin EJ, Ghovanloo MR, Zhao P, Dib-Hajj F, Randall AD, Waxman SG, Dib-Hajj SD.   +8 more
europepmc   +1 more source

Possible Anti-Pain Vaccines: A Narrative Review of Emerging Strategies and Clinical Prospects. [PDF]

Vaccines (Basel)
Martins YC, De-Sousa LP, Murin PJ, Sadeghipour H, Daniel-Ribeiro CT.   +4 more
europepmc   +1 more source

Pain management beyond opioids: a β-arrestin2-biased allosteric GPCR modulator opens new avenues for drug development. [PDF]

Signal Transduct Target Ther
Pottie E, Steinmüller SAM, Decker M.
europepmc   +1 more source

Virtual Screening-Guided Discovery of a Selective TRPV1 Pentapeptide Inhibitor with Topical Anti-Allergic Efficacy. [PDF]

Cells
Liu L, Hou W, He Q, Yuan F, Guo C, Liu R, Huang B, Wubulikasimu A, Rong M.   +8 more
europepmc   +1 more source

Unique electrophysiological property of a novel Nav1.7, Nav1.8, and Nav1.9 sodium channel blocker, ANP-230.

Biochemical and Biophysical Research Communications - BBRC
Tatsuya Kamei, Takehiro Kudo, Hana Yamane, Fumiaki Ishibashi, Yoshinori Takada, Shigeyuki Honda, Yasuyo Maezawa, Kazuhito Ikeda, Yoshihiro Oyamada   +8 more
semanticscholar   +1 more source