Results 11 to 20 of about 338,402 (262)
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Digital Actuation Control of Soft Robotic Origami With Self‐Folding Liquid Crystal Elastomer Hinges
Advanced Functional Materials, EarlyView.Self‐folding soft‐rigid hybrid robotic origami is enabled by liquid crystal elastomer actuators with embedded Joule heating and closed‐loop digital control. Digitally addressable hinges provide reversible and programmable transitions between distinct folded states while maintaining actuation performance at high cycle counts (over 1500).
David C. Bershadsky +3 more
wiley +1 more source
Orbital Geometry‐Governed Response of Pressure‐Tunable Quantum Defects in hBN
Advanced Functional Materials, EarlyView.Defects in hBN act as ultrasensitive quantum manometers when the energy of the intradefect optical transitions is modified by lattice compression. The orbital geometry of the electron wave functions governs how electron hopping and Coulomb interactions react uniquely to the reduction of the van der Waals gap and in‐plane compression, leading to robust ...
Magdalena Grzeszczyk +6 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Deployable medical devices typically need external stimuli to trigger deployment. However, external stimuli are difficult to supply within tissues. Here, we describe a strategy to deploy small‐scale structures into soft tissues after insertion without the need for any stimulus. We demonstrate deployment within a tissue phantom.
Yeh‐Chia Tseng +13 more
wiley +1 more source
Enhanced Endoscopic Internal Drainage of Gastric Abscess Through Additively Manufactured Stents
Advanced Healthcare Materials, EarlyView.Postoperative gastric leaks are often treated with off‐label biliary double‐pigtail stents, yet conventional extruded designs are not optimized for leak anatomy, can migrate, and may limit abscess evacuation. PETALS is introduced to optimize transmural drainage geometry and enable patient‐specific 3D‐printable stents.
Parima Phowarasoontorn +14 more
wiley +1 more source
Intelligent Acousto‐Electrical Metamaterials (IAM) for Sound Source Detection
Advanced Materials, EarlyView.Our proposed metamaterial concept enables sound source detection using a single material, in contrast to conventional arrays that require dozens or even hundreds of transducers. We show that the coupled acoustic–vibrational–electrical responses in piezoelectric metamaterials give rise to topology‐governed charge transport, producing distinct voltage ...
Victor Couëdel +7 more
wiley +1 more source
Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization
Advanced Materials, EarlyView.A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab +8 more
wiley +1 more source
Liquids as Reinforcements for Anisotropic and Tough Soft Matter Composites
Advanced Materials, EarlyView.Liquid metal droplets are shaped and oriented within soft elastomers to create all‐soft matter composites with programmable mechanical anisotropy. These liquid inclusions act as fiber‐like reinforcements, enabling directional stiffness, enhanced toughness, and controlled crack steering under extreme deformation, offering new routes to resilient soft ...
Gwyneth M. Schloer +5 more
wiley +1 more source
“Torpedo: Inventing the Military-Industrial Complex in the United States and Great Britain (Book Review)” by Katherine C. Epstein [PDF]
, 2016 Review of Torpedo: Inventing the Military-Industrial Complex in the United States and Great Britain by Katherine C ...
Isinger, Russell
core +1 more source