Inhibition of Rac1 attenuates radiation-induced lung injury while suppresses lung tumor in mice
Cell Death Discovery, 2022 The lung is one of the most sensitive tissues to ionizing radiation, thus, radiation-induced lung injury (RILI) stays a key dose-limiting factor of thoracic radiotherapy. However, there is still little progress in the effective treatment of RILI.
Ni An +10 more
doaj +1 more source
Symposium on Intracellular pH, PCO₂ and PO₂: Introductory Remarks [PDF]
, 1967 It is a pleasure to welcome the three authorities who will carry the major load of presentations in our symposium today. They are Dr. Frans Jöbsis of Duke University School of Medicine, Dr. Eugene Robin of The University of Pittsburgh School of Medicine,
Patterson, John L., Jr.
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Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Journal of Experimental & Clinical Cancer Research, 2023 Background Neoadjuvant radiotherapy has been used as the standard treatment of colorectal cancer (CRC). However, radiotherapy resistance often results in treatment failure.
Tingting Liu +16 more
doaj +1 more source
Medicine Infected by Politics: The American Occupation of Haiti, 1915-1934 [PDF]
, 2019 This article discusses the impact that politics and social beliefs have on the humanitarian goals of medicine, using the American occupation of Haiti (1915-1934) as a backdrop.
Scherr, Cooper
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Acute Jaundice in a Six-year-old: An Unusual Presentation of Atypical Kawasaki Disease [PDF]
, 2020 Kawasaki disease (KD) is a rare vasculitis of childhood that is critical to recognize and treat due to associated morbidity and mortality. A six-year-old male presented to our emergency department (ED) afebrile but with reported recent fevers.
Bylund, LCDR William +2 more
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Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Motion Sickness Symptomatology of Labyrinthine Defective and Normal Subjects During Zero Gravity Maneuvers [PDF]
, 1964 Motion sickness symptomology of labyrinthine defective and normal human subjects during zero gravity ...
Graybiel, A. +2 more
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Comparing Levels of Fitness of Police Officers between Two United States Law Enforcement Agencies Journal of Sports Medicine and Physical [PDF]
, 2018 BACKGROUND: The general physical task demands of law enforcement may suggest that police Officers are of similar fitness levels across cities, states and countries.OBJECTIVE: To investigate whether fitness levels of police Officers from two different ...
Dawes, James +7 more
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Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling
Advanced Healthcare Materials, EarlyView.Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee +7 more
wiley +1 more source