Results 31 to 40 of about 3,927,016 (290)

Inhibition of Rac1 attenuates radiation-induced lung injury while suppresses lung tumor in mice

Cell Death Discovery, 2022
The lung is one of the most sensitive tissues to ionizing radiation, thus, radiation-induced lung injury (RILI) stays a key dose-limiting factor of thoracic radiotherapy. However, there is still little progress in the effective treatment of RILI.
Ni An, Zhenjie Li, Xiaodi Yan, Hainan Zhao, Yajie Yang, Ruling Liu, Yanyong Yang, Fu Gao, Bailong Li, Hu Liu, Hongbin Yuan   +10 more
doaj   +1 more source

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

Advanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen, Rong Chen, Wei Li, Bin Song, Ruiying Zhang, Lewei Dai, Yuwei Qi, Ruqian Chen, Yifan Xu, Hangbin Li, Jingyi Huang, Fangping Wu, Jianan Peng, Xinyu Wang, Yang Xiong, Chaofeng Mu, Guilin Cheng, Zhaoshen Li, Shanming Ruan, Lei Huang, Mancang Gu   +20 more
wiley   +1 more source

Naval Postgraduate School Motorcycle Club [PDF]

, 1974
Originally published in The Classmate Magazine (1961-2001), initially a publication of the Naval Postgraduate School's Officer Students' Wives ...
Classmate Magazine, Wilder, Fred N.
core   +1 more source

Naval Research Working Group - April 9-11, 2019 [video]

, 2019
The Naval Postgraduate School (NPS) Naval Research Program (NRP) is funded by the Chief of Naval Operations and supports research projects for the Navy and Marine Corps.
Naval Postgraduate School
core   +1 more source

Migrasome: a new functional extracellular vesicle

Cell Death Discovery, 2023
Migrasome is a novel cellular organelle produced during cell migration, and its biogenesis depends on the migration process. It is generated in a variety of cells such as immune cells, metastatic tumor cells, other special functional cells like podocytes
Xide Zhang, Liuhuan Yao, Yuanyuan Meng, Bailong Li, Yanyong Yang, Fu Gao   +5 more
doaj   +1 more source

Machine Learning for Green Solvents: Assessment, Selection and Substitution

Advanced Science, EarlyView.
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta, Janhavi Nistane, Abhishek Sose, Harikrishna Sahu, Rampi Ramprasad   +4 more
wiley   +1 more source

80th anniversary of the birthday of naval doctor, doctor of medical sciences, professor Yuriy Evlampievich Barachevskiy

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
The article is dedicated to the 80th anniversary of the naval doctor, retired colonel of the medical service, full academician of the Academy of Military Sciences of the Russian Federation, doctor of medical sciences, professor Yuri Evlampievich ...
A. V. Andreeva, R. I. Belyaeva, I. M. Kobelev, G. O. Samburov, G. B. Chetskaya   +4 more
doaj   +1 more source

SENP5 promotes homologous recombination-mediated DNA damage repair in colorectal cancer cells through H2AZ deSUMOylation

Journal of Experimental & Clinical Cancer Research, 2023
Background Neoadjuvant radiotherapy has been used as the standard treatment of colorectal cancer (CRC). However, radiotherapy resistance often results in treatment failure.
Tingting Liu, Hang Wang, Yuanyuan Chen, Zhijie Wan, Zhipeng Du, Hui Shen, Yue Yu, Shengzhe Ma, Ying Xu, Zhuqing Li, Nanxi Yu, Fangxiao Zhang, Kun Cao, Jianming Cai, Wei Zhang, Fu Gao, Yanyong Yang   +16 more
doaj   +1 more source

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

Advanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang, Jianhua Li, Huilu Zhang, Qi Qin, Yichen Huang, Xiaofan Tian, Chao Sun, Binbin Li, Zhengxin Wang, Xin Zhang   +9 more
wiley   +1 more source

Atomic Tuning of Metal‐Support Interactions for Pathway‐Selective CO2 Photoreduction on TiO2

Advanced Science, EarlyView.
Single‐atom Fe and Cu catalysts anchored on TiO2 steer photocatalytic CO2 reduction toward distinct pathways. Fe sites favor rapid *CO desorption and selective CO formation, whereas Cu sites stabilize *CHO intermediates, enabling deep reduction and C─C coupling. Combined spectroscopy and DFT calculations reveal how metal–support interactions and oxygen
Dongyun Kim, Wonjae Ko, Byoung‐Hoon Lee, Sanghoon Kim, Yun Do Kim, Hyunsoo Ahn, Yoon Jung, Chan Woo Lee, Kug‐Seung Lee, Eunhee Gong, Junho Lee, Minho Kim, Taeghwan Hyeon, Su‐Il In   +13 more
wiley   +1 more source