Results 31 to 40 of about 2,341,539 (282)

SENP5 promotes homologous recombination-mediated DNA damage repair in colorectal cancer cells through H2AZ deSUMOylation

Journal of Experimental & Clinical Cancer Research, 2023
Background Neoadjuvant radiotherapy has been used as the standard treatment of colorectal cancer (CRC). However, radiotherapy resistance often results in treatment failure.
Tingting Liu, Hang Wang, Yuanyuan Chen, Zhijie Wan, Zhipeng Du, Hui Shen, Yue Yu, Shengzhe Ma, Ying Xu, Zhuqing Li, Nanxi Yu, Fangxiao Zhang, Kun Cao, Jianming Cai, Wei Zhang, Fu Gao, Yanyong Yang   +16 more
doaj   +1 more source

Atomic Tuning of Metal‐Support Interactions for Pathway‐Selective CO2 Photoreduction on TiO2

Advanced Science, EarlyView.
Single‐atom Fe and Cu catalysts anchored on TiO2 steer photocatalytic CO2 reduction toward distinct pathways. Fe sites favor rapid *CO desorption and selective CO formation, whereas Cu sites stabilize *CHO intermediates, enabling deep reduction and C─C coupling. Combined spectroscopy and DFT calculations reveal how metal–support interactions and oxygen
Dongyun Kim, Wonjae Ko, Byoung‐Hoon Lee, Sanghoon Kim, Yun Do Kim, Hyunsoo Ahn, Yoon Jung, Chan Woo Lee, Kug‐Seung Lee, Eunhee Gong, Junho Lee, Minho Kim, Taeghwan Hyeon, Su‐Il In   +13 more
wiley   +1 more source

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

Advanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa, Jingjun Mo, Xiaotong Diao, Feng Xie, Tingting Wang, Haowen Zhao, Dalei Wu, Rolf Müller, Chengzhang Fu   +8 more
wiley   +1 more source

80th anniversary of the birthday of naval doctor, doctor of medical sciences, professor Yuriy Evlampievich Barachevskiy

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
The article is dedicated to the 80th anniversary of the naval doctor, retired colonel of the medical service, full academician of the Academy of Military Sciences of the Russian Federation, doctor of medical sciences, professor Yuri Evlampievich ...
A. V. Andreeva, R. I. Belyaeva, I. M. Kobelev, G. O. Samburov, G. B. Chetskaya   +4 more
doaj   +1 more source

ATR-binding lncRNA ScaRNA2 promotes cancer resistance through facilitating efficient DNA end resection during homologous recombination repair

Journal of Experimental & Clinical Cancer Research, 2023
Background Our previous study first showed that ATR-binding long noncoding RNA (lncRNA) is necessary for ATR function and promotes cancer resistance. However, the specific lncRNAs instrumental in ATR activation remain largely unclear, which limits our ...
Yuanyuan Chen, Hui Shen, Tingting Liu, Kun Cao, Zhijie Wan, Zhipeng Du, Hang Wang, Yue Yu, Shengzhe Ma, Edward Lu, Wei Zhang, Jianming Cai, Fu Gao, Yanyong Yang   +13 more
doaj   +1 more source

Behavioral guidance for non-medical volunteers in designated isolation facilities

Shanghai yufang yixue, 2022
Corona virus disease 2019 （COVID-19） has led to more than 500 million cases， including 6.19 million deaths. Mutated strains of SARS-CoV-2 （alpha， beta， gamma， delta and omicron） have successively emerged.
ZHAO Yue, LIN Jiansheng, HU Ming, FAN junyan, SHEN Jiaying, CHEN Hongsen, WANG Ruihua, HE Yida, ZHU Xiaoqiong, CAO Guangwen   +9 more
doaj   +1 more source

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

Advanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray, Andrew R. Castillo, Manoj Kolel‐Veetil, Surya R. Kalidindi   +3 more
wiley   +1 more source

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

Advanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source

A Sprayable Nanoplatform Breaks the Vicious Cycle of Diabetic Wounds via Photoactivated Antioxidant and Drug Delivery

Advanced Science, EarlyView.
A sprayable near‐infrared‐activated nanoplatform incorporating MXene, ZnHCF nanozyme, and deferoxamine efficiently breaks the vicious cycle of diabetic wounds. Upon irradiation, interfacial electron transfer and photothermal effects enhance multi‐enzyme activity, enabling explosive ROS elimination, alleviation of hypoxia, and controlled DFO release ...
Jiahao Guo, Yuanyuan Meng, Qixiang Gui, Xi‐Tao Yang, Yong Fan, Xiaodong Zhu   +5 more
wiley   +1 more source

Layer‐Dependent Phonon Polaritons in hBN Resolved by Photo‐Induced Force Spectroscopy

Advanced Science, EarlyView.
Layer‐dependent phonon polariton resonances in hexagonal boron nitride are systematically investigated using photo‐induced force microscopy. The in‐plane resonance exhibits a blueshift, while the out‐of‐plane resonance shows a redshift with increasing thickness. These results establish layer number as a key parameter for tuning polaritonic responses in
Amin Hajarian, Jiwoo Seo, SungWoo Nam
wiley   +1 more source