Results 101 to 110 of about 429,163 (318)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

An Anti-Occlusion Approach for Enhanced Unmanned Surface Vehicle Target Detection and Tracking with Multimodal Sensor Data

Journal of Marine Science and Engineering
Multimodal sensors are often employed by USVs (unmanned surface vehicles) to enhance situational awareness, and the fusion of LiDAR and monocular vision is widely used in near-field perception scenarios.
Minjie Zheng, Dingyuan Li, Guoquan Chen, Weijun Wang, Shenhua Yang   +4 more
doaj   +1 more source

Implicit Measures of Lostness and Success in Web Navigation [PDF]

, 2007
In two studies, we investigated the ability of a variety of structural and temporal measures computed from a web navigation path to predict lostness and task success. The user’s task was to find requested target information on specified websites. The web
Ian Spence, Gwizdka, Jacek, Spence, Ian, Jacek Gwizdka   +3 more
core  

Navigating a revision [PDF]

BMJ Quality & Safety, 2010
There is the story—probably apocryphal—of the avid sailor, a retired physician, who lives on the Northeast US Atlantic coast and is said to host an unusual annual autumn beachfront gathering. His closest friends join him for the burning to the ground of a beloved sailing craft, generally a small wooden boat that he had spent the previous winter ...
openaire   +2 more sources

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Ship Autonomous Berthing Strategy Based on Improved Linear-Quadratic Regulator

Journal of Marine Science and Engineering
There has been significant interest in the research field of ship automatic navigation, particularly in the area of autonomous berthing. To address the key challenges of path planning and control during ship berthing, we propose an enhanced Linear ...
Jian Yin, Guoquan Chen, Shenhua Yang, Zeyang Huang, Yongfeng Suo   +4 more
doaj   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Real-Time Monitoring Method for Traffic Surveillance Scenarios Based on Enhanced YOLOv7

Applied Sciences
Due to the impact of scale variation of vehicle targets and changes in traffic environments in large-scale traffic monitoring systems, vehicle target detection methods often face challenges.
Dexin Yu, Zimin Yuan, Xincheng Wu, Yipen Wang, Xiaojia Liu   +4 more
doaj   +1 more source

Ultrasound-aided pedestrian dead reckoning for indoor navigation [PDF]

, 2008
Ad hoc solutions for tracking and providing navigation support to emergency response teams is an important and safety-critical challenge. We propose a navigation system based on a combination of foot-mounted inertial sensors and ultrasound beacons.
Mike Hazas, Hazas, Mike, Muthukrishnan, Kavitha, Kavitha Muthukrishnan, Hans Gellersen, Carl Fischer, Fischer, Carl, Hazas, Michael, Gellersen, Hans   +8 more
core   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source