Results 51 to 60 of about 429,163 (318)

Improvement of the real-time gesture analysis by a new mother wavelet and the application for the navigation inside a scale-one 3D system [PDF]

open access: yes, 2013
This paper proposes a navigation technique for traveling inside a real-scale 3D model based on human gesture analysis. In the first step, a simple threshold is used as a criterion to analyze gestures.
CHARDONNET, Jean-Rémy   +7 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Analysis of GNSS disruptions in European airspace [PDF]

open access: yes, 2023
Global navigation satellite systems have enabled significant improvements in aeronautical navigation over the past decades. However, in recent years a growing number of radio frequency interference events been reported by flight crews rendering this ...
Strohmeier, Martin   +5 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Finite-time ship formation control based on extended state observer

open access: yesZhongguo Jianchuan Yanjiu, 2023
ObjectiveIn order to solve the problems of most current ship formation control algorithms such as their long control cycle and poor timeliness, this paper proposes a finite-time control strategy based on an extended state observer (ESO).MethodsFirst, a ...
Jun NING   +5 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

COLREGS-based Path Planning for Ships at Sea Using Velocity Obstacles

open access: yesIEEE Access, 2021
Recent studies have made significant development in path planning for ships. However some studies blindly obey rules of COLREGS (International Regulations for Preventing Collisions at Sea) or only adopt turning to starboard ignoring actual practice, like,
Wenjun Zhang   +6 more
doaj   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Magnetic PDMS@SiO2/Fe3O4 composite friction layer material for enhanced triboelectric nanogenerator output performance

open access: yesScience and Technology for Energy Transition
Triboelectric nanogenerators (TENG) have exhibited remarkable potential in harnessing stochastic low-frequency mechanical energy from oceanic surfaces, attributed to their versatile architectures and capability for extensive deployment.
Zhang Shaojun   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy