Results 151 to 160 of about 150,411 (276)
ABSTRACT Aim To characterise nurses' perspectives on factors that influence their ability to provide patient‐centered nursing care for autistic patients in a large urban hospital setting. Design Qualitative exploratory study. Methods We conducted semi‐structured interviews via Zoom with nurses from a large urban hospital serving primarily adult ...
Amy Watson‐Grace +7 more
wiley +1 more source
Gestational kynurenine metabolites mediate effects of pregnancy adiposity on child negative affect
Background Mounting evidence links increased adiposity during pregnancy and offspring risk for mental health disorders. Yet the mechanisms underlying this association remain poorly understood, limiting our ability to design effective interventions.
Hanna C. Gustafsson +4 more
wiley +1 more source
Backstory on the NCATS and AZ/MRC structures paper
Updates, 11 Jan 2013, a) an orthogonal backstory from one of my esteemed co-authors b) I am pleased to be involved in the planning of a repurposing workshop at BioIT 2013, April, in Boston. One of the benefits of blogging is to be able to add extra bits of context to your own papers, in this case "Challenges and ...
openaire +1 more source
scRNA‐Seq reveals anti‐lymphoma immune responses in mogamulizumab‐associated skin eruptions
CCR4 was expressed in malignant clones and regulatory T cells in untreated CTCL, that were decreased in MAR. Malignant clones in MAR showed a silenced phenotype with decreases in central memory markers SELL and CCR7, and GTP‐binding member GIMAP7 and upregulation of MMP2 inhibitor TIMP2 and tumour suppressor gene RUNX3.
Shannon Meledathu +13 more
wiley +1 more source
ABSTRACT Background Delirium afflicts 17% of older emergency department (ED) patients and 25% of older hospitalized patients. This form of acute brain failure is associated with accelerated cognitive decline. We conducted a randomized controlled trial to determine whether early cognitive intervention improved 4‐month global cognition in older ED ...
Jin H. Han +15 more
wiley +1 more source
Novel and emerging antimicrobial strategies in the management of oral infections
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley +1 more source
Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK [PDF]
Austin, Christopher P. +8 more
core +2 more sources
MRC 22 vs. NCATS 58 repurposing lists: similar but different
Update, December, we have a paper out on the results. The collaboration between the MRC and AstraZeneca to give UK academic researchers access to development compounds has been acknowledged as a precedent for the compilation of the analogous NCATS 58-set from multiple companies. A snapshot of the MRC list of 22 is shown below.
openaire +1 more source
Quantitative Diffusion and T2 Mapping Using RF‐Modulated Phase‐Based Gradient Echo Imaging
ABSTRACT Purpose To introduce and evaluate the feasibility of a novel RF‐phase modulated gradient echo (GRE) method for quantitative diffusion MRI, aimed at mitigating geometric distortion and enabling high‐resolution 3D quantitative diffusion/T2 mapping as a complementary alternative to conventional DWI.
Daiki Tamada +4 more
wiley +1 more source
A Homogeneously Catalyzed Paired Electrolytic Cell for Hydrogen Peroxide Production
Cu(tmpa) and Sn‐TMPyP are compatible and efficient catalysts for 2e−‐ORR and 2e−‐WOR, respectively, which have been employed to assemble an efficient paired electrochemical cell for H2O2 production. The presence of a carbonate buffer is essential to achieve a high activity in the anode compartment, while control over mass transport is essential for a ...
Caterina Trotta +7 more
wiley +2 more sources

