Results 41 to 50 of about 81,769 (307)

NEQUIM Contact System (NCS): A tool for generation and analysis of protein-ligand interaction fingerprint [PDF]

NEQUIM Contact System (NCS) is a system to generate and analyze interaction vectors of protein-ligand complexes. Core features include multiple views of vectors, multiple selection options, cluster analysis and the generation of interaction vector models.
Andrelly , Martins-José, Julio, Lopes
core   +1 more source

Level of knee functional limitations among patients after knee arthroscopy: a cross-sectional study

Bulletin of Faculty of Physical Therapy
Introduction Knee joint disorders are prevalent musculoskeletal conditions that frequently impair daily functional capacity. Arthroscopy, a minimally invasive surgical technique, is widely utilized for the diagnostic and therapeutic management of knee ...
Hazrat Bilal, Bilal Ahmad, Danyal Muhammad, Zahoor Ahmad, Abdullah Jehangir, Irfan Ahmad   +5 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Interfacial reaction of mixed pure metal powders under microwave heating

Journal of Materials Research and Technology
To investigate the interfacial reaction of metal powder after absorbing microwave radiation, pure metal powder composed of five elements, Fe, Co, Ni, Cr, and Mn, was microwave heated at four temperature gradients of 500, 800, 1000, and 1200 °C.
Xuebin Chen, Lei Zhao, Lixia Yang, Xuejing Shen, Jingwei Yang, Haizhou Wang   +5 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

A comparative study of progression in the topic matter and materials across the NCS, the NCS work schedule and the CAPS [PDF]

, 2012
Includes abstract.Includes bibliographical references.The following research report is based on a project that compares progression in the topic of Matter and Materials in the Natural Sciences Grade R-9 content framework as it is represented in the ...
Aploon-Zokufa, Kaylianne
core   +1 more source

Effectiveness of Chest Physical Therapy in Improving Quality of Life and Reducing Patient Hospital Stay in Chronic Obstructive Pulmonary Disease

Journal of the Dow University of Health Sciences, 2018
Objective: To find out the effectiveness of chest physical therapy along with standard medical treatment versus standard medical treatment alone in improving quality of life and reducing patient's hospital stay in Chronic Obstructive Pulmonary Disease ...
Waleed Khan, Aatik Arsh, Syed Muhammad Hammad, Syed Arif Shah, Shahid Khan, Abdul Haq   +5 more
doaj   +1 more source

The Structure of NC-Groups

Journal of Algebra, 2001
A finite group \(G\) is called an NC-group if \(C_G(A)=N_G(A)\) or \(C_G(A)=A\) for every Abelian subgroup \(A\) of \(G\). These groups are completely classified in this paper: apart from \(A_5\) and \(\text{PSL}(2,7)\), which are the only nonsolvable NC-groups, there are 6 more classes of solvable ones.
openaire   +2 more sources

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source