Results 31 to 40 of about 901,770 (288)

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

A Comparative Study on New Design Fixation Plate for Parasymphysis of Mandible Fracture with Conventional System

Journal of Pharmacy and Bioallied Sciences
Background: A new non-compression MP has been developed that offers similar benefits to 3D plates and is easier to fix in the PS region (R), as the conceptual design of the plates will allow fx in the PSR while retaining the 3D geometry of the plate. Aim:
Yusuf Ronad, CH V K N S N Moorthy, Pratap Mane, Lishoy W. Rodrigues, Sana Anwar, Dhanu Priya Patel   +5 more
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

The Use of Reproductive Health Information Material in the Rural Clinics of Umtata District

Curationis, 1999
Though it appears that there has been a long history of development .distribution and dissemination of reproductive health information materials, impediments still exist in the health information .communication and education systems in South Africa.
ND Mbananga
doaj   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Assessing the Utility of an Electronic Research Database to Capture Whole Systems Practice at Two Naturopathic Outpatient Teaching Clinics

Journal of Evidence-Based Complementary & Alternative Medicine, 2013
This observation study assessed the utility of an electronic Naturopathic Patient Database at 2 naturopathic teaching clinics as a research and educational tool.
Brenda M. Y. Leung ND, MSc, Gillian Flower ND, BA, Kieran Cooley ND, MSc, Chris Habib ND, MSc, Matt Gowan ND, Stefan Podgrabinski, Dugald Seely ND, MSc   +6 more
doaj   +1 more source

2 nd Brazilian Consensus on Chagas Disease, 2015.

Revista da Sociedade Brasileira de Medicina Tropical, 2016
Chagas disease is a neglected chronic condition with a high burden of morbidity and mortality. It has considerable psychological, social, and economic impacts.
J. Dias, Alberto Novaes Ramos Junior, E. D. Gontijo, A. Luquetti, M. Shikanai-Yasuda, J. Coura, R. M. Torres, J. R. Melo, E. A. Almeida, W. Oliveira, A. C. Silveira, J. Rezende, Fabiane Scalabrini Pinto, Antonio Walter Ferreira, A. Rassi, A. Fragata, A. Sousa, D. Correia, A. Jansen, Gláucia Manzan Queiroz de Andrade, C. Britto, A. Y. Pinto, A. Rassi, Dayse Elisabeth Campos, F. Abad‐Franch, S. Santos, E. Chiari, A. Hasslocher-Moreno, E. F. Moreira, D. S. O. Marques, Eliane Lages Silva, J. Marin-Neto, L. Galvão, S. Xavier, S. A. Valente, N. B. Carvalho, A. Cardoso, R. A. Silva, V. M. Costa, S. Vivaldini, S. Oliveira, V. Valente, M. Lima, R. V. Alves   +43 more
semanticscholar   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Рениеносные медно-порфировые системы Урала: геологическое положение, изотопно- петрогеохимическая и возрастная латеральная зональность

Литосфера, 2019
В настоящее время Урал можно рассматривать как новую промышленную медно-порфировую провинцию России (открыты месторождения, содержащие 1-2 млн. т меди и, возможно, более).

doaj  

DEFINING SIMPLE nD OPERATIONS BASED ON PRISMATIC nD OBJECTS [PDF]

ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2016
Abstract. An alternative to the traditional approaches to model separately 2D/3D space, time, scale and other parametrisable characteristics in GIS lies in the higher-dimensional modelling of geographic information, in which a chosen set of non-spatial characteristics, e.g. time and scale, are modelled as extra geometric dimensions perpendicular to the
K. Arroyo Ohori, H. Ledoux, J. Stoter
openaire   +4 more sources