Results 41 to 50 of about 3,616,635 (270)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Рениеносные медно-порфировые системы Урала: геологическое положение, изотопно- петрогеохимическая и возрастная латеральная зональность

open access: yesЛитосфера, 2019
В настоящее время Урал можно рассматривать как новую промышленную медно-порфировую провинцию России (открыты месторождения, содержащие 1-2 млн. т меди и, возможно, более).

doaj  

Germination seeds of millet genotypes under the influences of PEG 6000 solution on the 3d and 6th days

open access: yesPlant Varieties Studying and Protection, 2020
Purpose. To determine the drought resistance of five millet varieties (ʻOmriyaneʼ, ʻKharkivske 57ʼ, ʻKonstantinovskeʼ, ʻIR 5ʼ, ʻSlobozhanskeʼ) using PEG 6000 as osmotic stress. Methods.
О. В. Горлачова   +3 more
doaj   +1 more source

Prevalence and Trends of Basic Activities of Daily Living Limitations in Middle-Aged and Older Adults in the United States

open access: yesEpidemiologia, 2023
Background: Population-level surveillance of the prevalence and trends of basic self-care limitations will help to identify the magnitude of physical disablement in the rapidly growing older American demographic.
Halli Heimbuch   +6 more
doaj   +1 more source

Application of a Dy3Co0.6Cu0.4Hx addition for controlling the microstructure and magnetic properties of sintered Nd-Fe-B magnets [PDF]

open access: yes, 2019
The focus of new technologies on the formation of inhomogeneous distributions of heavy rare-earth metals (REMs) in hard magnetic Nd-Fe-B materials is of scientific importance to increase their functional properties, along with preserving existing sources
Burkhanov, Gennadij Sergeevich   +9 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

L'éducation thérapeutique en néonatalogie: remédier au stress et aux incertitudes des parents : revue de la littérature [PDF]

open access: yes, 2015
Contexte : En 2013, l’OFSI chiffre la prématurité à 7,2% de la population Suisse. L’événement que représente une naissance prématurée éveille de nombreuses incertitudes chez les néo-parents. Le milieu hospitalier hautement spécialisé provoque stress et
Karasavvidis, Savvas, Morard, Adélaïde
core  

Panda: Neighbor Discovery on a Power Harvesting Budget

open access: yes, 2016
Object tracking applications are gaining popularity and will soon utilize Energy Harvesting (EH) low-power nodes that will consume power mostly for Neighbor Discovery (ND) (i.e., identifying nodes within communication range).
Chen, Tingjun   +4 more
core   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

High Performance Negative Database for Massive Data Management System of The Mingantu Spectral Radioheliograph

open access: yes, 2017
As a dedicated synthetic aperture radio interferometer, the MingantU SpEctral Radioheliograph (MUSER), initially known as the Chinese Spectral RadioHeliograph (CSRH), has entered the stage of routine observation. More than 23 million data records per day
Deng, Hui   +5 more
core   +1 more source

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