Results 31 to 40 of about 3,616,635 (270)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Treating Type 2 Diabetes: A Cross-sectional Audit of Naturopathic Standards of Care Using the Naturopathic Patient Database

Journal of Evidence-Based Complementary & Alternative Medicine, 2012
The Naturopathic Patient Database is a data management tool developed by the Canadian College of Naturopathic Medicine to collect patient data from its teaching clinic, the Robert Schad Naturopathic Clinic.
Christopher Habib ND, Matthew Gowan ND, Stefan Podgrabinski, Tom Grodski ND, Brenda Leung ND, Maria Shapoval ND, Dugald Seely MSc, Kieran Cooley ND   +7 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

A Comparative Study on New Design Fixation Plate for Parasymphysis of Mandible Fracture with Conventional System

Journal of Pharmacy and Bioallied Sciences
Background: A new non-compression MP has been developed that offers similar benefits to 3D plates and is easier to fix in the PS region (R), as the conceptual design of the plates will allow fx in the PSR while retaining the 3D geometry of the plate. Aim:
Yusuf Ronad, CH V K N S N Moorthy, Pratap Mane, Lishoy W. Rodrigues, Sana Anwar, Dhanu Priya Patel   +5 more
doaj   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

The Use of Reproductive Health Information Material in the Rural Clinics of Umtata District

Curationis, 1999
Though it appears that there has been a long history of development .distribution and dissemination of reproductive health information materials, impediments still exist in the health information .communication and education systems in South Africa.
ND Mbananga
doaj   +1 more source

Renormalized parameters and perturbation theory for an n-channel Anderson model with Hund's rule coupling: Asymmetric case

, 2010
We explore the predictions of the renormalized perturbation theory for an n-channel Anderson model, both with and without Hund's rule coupling, in the regime away from particle-hole symmetry.
A. C. Hewson, A. C. Hewson, D. J. G. Crow, Y. Nishikawa   +3 more
core   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Assessing the Utility of an Electronic Research Database to Capture Whole Systems Practice at Two Naturopathic Outpatient Teaching Clinics

Journal of Evidence-Based Complementary & Alternative Medicine, 2013
This observation study assessed the utility of an electronic Naturopathic Patient Database at 2 naturopathic teaching clinics as a research and educational tool.
Brenda M. Y. Leung ND, MSc, Gillian Flower ND, BA, Kieran Cooley ND, MSc, Chris Habib ND, MSc, Matt Gowan ND, Stefan Podgrabinski, Dugald Seely ND, MSc   +6 more
doaj   +1 more source

Identifying the origins of local atmospheric deposition in the steel industry basin of Luxembourg using the chemical and isotopic composition of the lichen Xanthoria parietina [PDF]

, 2008
Trace metal atmospheric contamination was assessed in one of the oldest European industrial sites of steel production situated in the southern part of the Grand-Duchy of Luxembourg.
Geagea, Majdi Lahd, Hissler, Christophe, Hoffmann, Lucien, Krein, Andreas, Perrone, Thierry, Probst, Jean-Luc, Stille, Peter   +6 more
core   +4 more sources