The evolutionary history of human spindle genes includes back-and-forth gene flow with Neandertals [PDF]
eLife, 2022 Proteins associated with the spindle apparatus, a cytoskeletal structure that ensures the proper segregation of chromosomes during cell division, experienced an unusual number of amino acid substitutions in modern humans after the split from the ...
Stéphane Peyrégne +3 more
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Optimal linear estimation models predict 1400–2900 years of overlap between Homo sapiens and Neandertals prior to their disappearance from France and northern Spain [PDF]
Scientific Reports, 2022 Recent fossil discoveries suggest that Neandertals and Homo sapiens may have co-existed in Europe for as long as 5 to 6000 years. Yet, evidence for their contemporaneity at any regional scale remains highly elusive. In France and northern Spain, a region
Igor Djakovic +2 more
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Midfacial Morphology and Neandertal–Modern Human Interbreeding [PDF]
Biology, 2022 Ancient DNA from, Neandertal and modern human fossils, and comparative morphological analyses of them, reveal a complex history of interbreeding between these lineages and the introgression of Neandertal genes into modern human genomes.
Steven E. Churchill +2 more
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Variation in cross-sectional indicator of femoral robusticity in Homo sapiens and Neandertals [PDF]
Scientific Reports, 2022 Variations in the cross-sectional properties of long bones are used to reconstruct the activity of human groups and differences in their respective habitual behaviors.
Anna Maria Kubicka +6 more
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Highly selective cannibalism in the Late Pleistocene of Northern Europe reveals Neandertals were targeted prey [PDF]
Scientific ReportsThe Troisième caverne of Goyet has yielded the largest assemblage of Neandertal remains in Northern Europe with clear evidence of anthropogenic modifications.
Quentin Cosnefroy +10 more
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Rapid change in red cell blood group systems after the main Out of Africa of Homo sapiens [PDF]
Scientific ReportsDespite the advances in paleogenomics, red cell blood group systems in ancient human populations remain scarcely known. Pioneer attempts showed that Neandertal and Denisova, two archaic hominid populations inhabiting Eurasia, expressed blood groups ...
Stéphane Mazières +3 more
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Muscle AMP deaminase activity was lower in Neandertals than in modern humans [PDF]
Nature CommunicationsThe enzyme AMPD1 is expressed in skeletal muscle and is involved in ATP production. All available Neandertal genomes carry a lysine-to-isoleucine substitution at position 287 in AMPD1.
Dominik Macak +6 more
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Major Genetic Risk Factors for Dupuytren's Disease Are Inherited From Neandertals [PDF]
Molecular Biology and Evolution, 2023 Masahiro Kanai +2 more
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The date of interbreeding between Neandertals and modern humans. [PDF]
PLoS Genetics, 2012 Comparisons of DNA sequences between Neandertals and present-day humans have shown that Neandertals share more genetic variants with non-Africans than with Africans.
Sriram Sankararaman +4 more
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Reduced purine biosynthesis in humans after their divergence from Neandertals
eLife, 2021 We analyze the metabolomes of humans, chimpanzees, and macaques in muscle, kidney and three different regions of the brain. Although several compounds in amino acid metabolism occur at either higher or lower concentrations in humans than in the other ...
Vita Stepanova +25 more
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