Results 71 to 80 of about 446,310 (340)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Detection of inner Solar System Trojan Asteroids by Gaia [PDF]

, 2012
The Gaia satellite, planned for launch by the European Space Agency (ESA) in 2013, is the next generation astrometry mission following Hipparcos. While mapping the whole sky, the Gaia space mission is expected to discover thousands of Solar System ...
Coward, D. M., Tanga, P., Todd, M., Zadnik, M. G.   +3 more
core   +3 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Automated detection of asteroids in real-time with the Spacewatch telescope [PDF]

The Spacewatch telescope on Kitt Peak is being used to survey for near-earth asteroids using a Tektronix TK2048 CCD in scanning mode. We hope to identify suitable low delta v candidates amongst the near-earth asteroid population as possible exploration ...
Gehrels, T., Rabinowitz, David L., Scotti, James Vernon   +2 more
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Identifying LL Chondrite Near-Earth Asteroids Using LL Chondrite Reflectance Spectra

The Astrophysical Journal Letters
Most near-Earth objects are thought to originate from the collisional fragments of the main asteroid belt. One question that remains to be resolved is the proportion of near-Earth objects sampling the core area material of the parent body to the outer ...
Pengyue Wang, Edward Cloutis, Ye Su, Man-To Hui   +3 more
doaj   +1 more source

HIGH-PRECISION FOLLOW-UP OBSERVATIONS OF NEAR-EARTH OBJECTS

Odessa Astronomical Publications, 2018
Main objective of the study is orbit refinement of Near-Earth Objects (NEOs) as part of the global task of asteroid-cometary hazard. We present the latest results of ongoing high-precision astrometric follow-up observations of NEOs using the Mykolaiv ...
N. V. Maigurova, A. V. Pomazan, A. V. Shulga   +2 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Modeling Linear Polarization of the Didymos–Dimorphos System before and after the DART Impact

The Planetary Science Journal
We analyze the polarization observations of the Didymos–Dimorphos system before and after the impact by the NASA Double Asteroid Redirection Test spacecraft on Dimorphos.
Antti Penttilä, Karri Muinonen, Mikael Granvik, Zuri Gray, Stefano Bagnulo, Ludmilla Kolokolova, Fernando Moreno   +6 more
doaj   +1 more source

On the ballistic capture of asteroids for resource utilisation [PDF]

, 2011
This paper investigates the concept of capturing in the Earth’s neighbourhood Earth-approaching objects such as asteroids and comets. These objects may provide access to potential resources, as well as be potential scientific mission opportunities.
McInnes, C.R., Sanchez Cuartielles, J.P.
core