Results 71 to 80 of about 599,165 (331)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Infrared Fluxes and Lightcurves of Near-Earth Objects: The Full Spitzer Sample

The Astronomical Journal
The IRAC camera on the Spitzer Space Telescope observed 2175 near-Earth objects (NEOs) during its Warm Mission phase, primarily in three large surveys, and also in a small number of a dedicated projects.
Joseph L. Hora, Alicia J. Allen, David E. Trilling, Howard A. Smith, Andrew McNeill   +4 more
doaj   +1 more source

A constellation of CubeSats with synthetic tracking cameras to search for 90% of potentially hazardous near-Earth objects [PDF]

, 2015
We present a new space mission concept that is capable of finding, detecting, and tracking 90% of near-Earth objects (NEO) with H magnitude of $\rm H\leq22$ (i.e., $\sim$140 m in size) that are potentially hazardous to the Earth.
M. Shao, S. Turyshev, Sara C. Spangelo, T. Werne, C. Zhai   +4 more
semanticscholar   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

FEATURES OF KOTLIN ORBIT ESTIMATION LIBRARY

Odessa Astronomical Publications, 2018
Since the launch of Sputnik 1, the number of objects in near-earth orbit has been constantly increasing. The growth of number of these objects increases the risk of their collisions with existing satellites and ones which will be launched, that can be ...
L. S. Shakun
doaj   +1 more source

Detection of inner Solar System Trojan Asteroids by Gaia [PDF]

, 2012
The Gaia satellite, planned for launch by the European Space Agency (ESA) in 2013, is the next generation astrometry mission following Hipparcos. While mapping the whole sky, the Gaia space mission is expected to discover thousands of Solar System ...
Coward, D. M., Tanga, P., Todd, M., Zadnik, M. G.   +3 more
core   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Observing Near-Earth Objects with the James Webb Space Telescope [PDF]

, 2015
The James Webb Space Telescope (JWST) has the potential to enhance our understanding of near-Earth objects (NEOs). We present results of investigations into the observability of NEOs given the nominal observing requirements of JWST on elongation (85°–135°
C. Thomas, P. Abell, J. Castillo‐Rogez, N. Moskovitz, M. Mueller, V. Reddy, A. Rivkin, E. Ryan, J. Stansberry   +8 more
semanticscholar   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source