Results 71 to 80 of about 14,583 (268)
Are Near Earth Objects the Key to Optimization Theory
British Journal of Mathematics & Computer Science, 2013 This note suggests that near earth objects and Central Force Optimization have something in common, that NEO theory may hold the key to solving some vexing problems in deterministic optimization: local trapping and proof of convergence. CFO analogizes Newton's laws to locate the global maxima of a function.
openaire +2 more sources
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
The Planetary Science JournalNear-Earth Object (NEO) Surveyor will detect asteroids and comets using mid-infrared thermal emission, however ground-based followup resources will require knowledge of the expected visible light brightness in order to plan characterization observations.
Joseph R. Masiero +4 more
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
The Planetary Science JournalThe OSIRIS-REx mission used stereophotoclinometry (SPC) to generate digital terrain models (DTMs) of its target asteroid, Bennu. Here we present a suite of preflight tests conducted to identify the observing geometry and number of images needed to create
Eric E. Palmer +11 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Placing the Near-Earth Object Impact Probability in Context
The Planetary Science JournalNear-Earth objects (NEOs) have the potential to cause extensive damage and loss of life on Earth. Advancements in NEO discovery, trajectory prediction, and deflection technology indicate that an impact could be prevented, with sufficient warning time. We
C. R. Nugent +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
The Population of Small Near-Earth Objects: Composition, Source Regions, and Rotational Properties
The Planetary Science JournalThe study of small (
Juan A. Sanchez +9 more
doaj +1 more source
Development of Radar and Optical Tracking of Near-Earth Asteroids at the University of Tasmania
Remote SensingWe detail the use of the University of Tasmania’s (UTAS) optical and radio telescopes to conduct observations of near-Earth asteroids from 2021 to 2024.
Oliver James White +11 more
doaj +1 more source