Results 41 to 50 of about 4,834,953 (288)

Hybrid Simulation of Near-Fault Ground Motion for a Potential Mw 7 Earthquake in Lebanon [PDF]

open access: yes, 2021
International audienceLebanon is a densely populated country crossed by major faults. Historical seismicity shows the potential of earthquakes with magnitudes >7, but large earthquakes have never been instrumentally recorded in Lebanon.
Mariscal, Armand   +7 more
core   +1 more source

Spectral element method simulation of three-dimensional sedimentary basin under reverse-fault earthquakes

open access: yes地震科学进展, 2020
Near-fault ground motion can cause serious earthquake disaster in the near-field area,especially when there is sedimentary topography in the area. At present,there are no reports on the ground motion response of sedimentary basins under the action of ...
Zhenning Ba   +4 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

A simplified method for determining the equivalent peak ground acceleration of near-fault pulse-like ground motions

open access: yesGeomatics, Natural Hazards & Risk
Near-fault ground motions (NFGMs) differ significantly from far-field ground motions (FFGMs), as NFGMs exhibit pronounced pulse effects and directionality.
Xianqing Cheng   +4 more
doaj   +1 more source

Study on the shock-absorbing effect of a new staggered story isolated structure under the long-period earthquake motion

open access: yesFrontiers in Earth Science, 2023
The finite element model of a new staggered story isolated structure is established. Using the time-history analysis method, the dynamic response state of the structure at each time step is calculated by integrating the acceleration time-history data ...
Tong Shu   +6 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Seismic remote sensing for the earthquake source process and near‐source strong shaking: A case study of the October 16, 1999 Hector Mine earthquake

open access: yesGeophysical Research Letters, 2000
A new methodology to automatically determine the earthquake source process and near‐source strong ground motions using regional and local distance data was used to study the October 16, 1999 Hector Mine earthquake (MW7.1).
Douglas Dreger, Anastasia Kaverina
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Coseismic displacement estimate of the 2013 M S7.0 Lushan, China earthquake based on the simulation of near-fault displacement field

open access: yesEarthquake Science, 2016
Usually, GPS observation provides direct evidence to estimate coseismic displacement. However, GPS stations are scattered, sparse and cannot provide a detailed distribution of coseismic displacement.
Hong Zhou
doaj   +1 more source

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