Results 151 to 160 of about 1,840,084 (313)
The motion of a singular vortex near an escarpment
McDonald (1998) has studied the motion of an intense, quasi-geostrophic, equivalent barotropic, singular vortex near an infinitely long escarpment. The present work considers the remaining cases of the motion of weak and moderate intensity singular ...
Johnson, ER, Dunn, DC, McDonald, NR
core
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Let KG be the group ring of a group G over a commutative ring K with unity. The rings KG are described for which xx(sigma)=x(sigma)x for all x=∑(g∈G)alfa(g)g∈KG, where x↦x(sigma)=∑(g∈G)alfa(g)f(g)sigma(g) is an involution of KG; here f:G→U(K) is a ...
Bódi, Viktor, Siciliano, S.
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
This paper is an attempt primarily to clarify and prove some of the statements left unproved by Gerald Berman and Robert J . Silverman in their article Near Rings which appeared in the January, 1959 issue of The American Mathematical Monthly, Vol.
Alchediak, Michael
core
Anti-Fuzzy Ideal in (m, n)-Near Rings
In this article, we introduce and discuss the definitions of fuzzy (m, n)-sub near rings, anti-fuzzy (m, n)- sub near rings, fuzzy ideals, and anti-fuzzy ideals in (m, n)-near rings.
Fahimeh Mohammadi, Bijan Davvaz
doaj
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Prior to 1990, the only well known ideal-hereditary Kurosh-Amitsur radicals in the variety of zero-symmetric near-rings were the Jacobson type radicals Iv(N) , where ∨∈{2,3} and the Brown-McCoy radical.
Mogae, Kabelo
core

