Results 51 to 60 of about 2,117,336 (305)

Bollettino delle attività del Museo del Vicino Oriente, Egitto e Mediterraneo della Sapienza, anno 2015 [PDF]

open access: yes, 2015
During its first year of life, the Museum of Near East, Egypt and Mediterranean has launched various activities such as seminars, conferences, concerts, in order to make the museum as a space for reflection and knowledge of the ancient cultures of the ...
Montanari, Daria
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

The Keasler site (41HS235), a Titus Phase Cemetery in the Little Cypress Creek Basin, Harrison County, Texas [PDF]

open access: yes, 2015
The Keasler site (41HS235) is a Late Caddo period, Titus phase (ca. A.D. 1430-1680) cemetery in the East Texas Pineywoods. The site was excavated by collectors in the late 1970s, including Red McFarland, one of the more active looters of Caddo burials in
Perttula, Timothy K.
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

The Impact of Macroeconomic Variables on Stock Returns: A Case of the Johannesburg Stock Exchange [PDF]

open access: yesRevista Română de Statistică, 2018
The study assessed association of macroeconomic variables: inflation (INF), Money supply growth (M3), Interest rates (IR) and USD ZAR exchange rate (EX) using quarterly data from the year 1981Q1 to 2016 Q4 on stock price for the Johannesburg Stock ...
Boldwin Ndlovu   +3 more
doaj  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Selected Properties of Overlaid Magnesium Based Composite Panels for Flooring

open access: yesApplied Sciences, 2020
The objective of this work was to evaluate some of the mechanical and physical properties of the flooring materials manufactured from panels having magnesia substrate overlaid with oak veneer (Querqus alba) and linoleum sheets.
Fidan Aslanova   +3 more
doaj   +1 more source

Evaluation of Ductility of Reinforced Concrete Structures with Shear Walls having Different Thicknesses and Different Positions

open access: yesInternational Islamic University Malaysia Engineering Journal, 2022
Ductility is one of the main criteria in reinforced concrete (RC) structures. ASCE 7-10 seismic design code recognizes the importance of ductility in earthquake-resistant structures.
Rifat Resatoglu, Shahram Jkhsi
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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