Results 111 to 120 of about 9,315,628 (295)

The End is Neat

, 2005
Cover for The End is Neat, from the RISD Library Zine Collection.https://digitalcommons.risd.edu/specialcollections_zinecollection/1665/thumbnail ...
McCardle, Michael, Collections, Special, Library, Fleet   +2 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Surfing for Inspiration: digital inspirational material in design practice [PDF]

, 2018
Over the last decade, many new opportunities have emerged to support creativity and problem-solving in design by finding inspirational materials via the Internet.
Laszlo, Magda, Koch, Janin, Andrés LUCERO, Lucero, Andrés, Antti OULASVIRTA, Oulasvirta, Antti, Magda LÁSZLÓ, Lucero Vera, Andres, Janin KOCH   +8 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

NEAT Architecture

, 2016
Ossification of the Internet transport-layer architecture is a significant barrier to innovation of the Internet. Such innovation is desirable for many reasons.
Bozakov, Zdravko, Ros, David (5086394), Papastergiou, Giorgos, Hansen, Audun Fosselie, Fairhurst, Gorry, Brunstrom, Anna (5086391), Eckert, Toerless (5086511), Welzl, Michael, Ros, David, Mangiante, Simone (5086406), Khademi, Naeem (5086403), Vyncke, Eric (5086502), Damjanovic, Dragana, Tüxen, Michael (5086400), Khademi, Naeem, Fairhurst, Gorry (5086412), Grinnemo, Jones, Tom (5086373), Bozakov, Zdravko (5086388), Evensen, Kristian Riktor (5086418), McManus, Patrick, Welzl, Michael (5086379), Eckert, Toerless, Mangiante, Simone, Brunstrom, Anna, Jones, Tom, Tüxen, Michael, Grinnemo (5086499), Hansen, Audun Fosselie (5086433), McManus, Patrick (5086508), Evensen, Kristian Riktor, Papastergiou, Giorgos (5086505), Vyncke, Eric, Damjanovic, Dragana (5086397)   +33 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Research on high-velocity ballistic impact of para-aramid sateen fabric with ZnO nanorods oriented to the development of soft body armor

Materials & Design
This study introduces an innovative approach of utilizing ZnO nanorod growing technology to the sateen fabric in order to improve its ballistic performance.
Yanyan Chu, Baokun Zhu, Xucai Wang, Shengnan Min, Hong Chen, Weihan Huang, Yue Zhang, Tao Peng, Xiaogang Chen   +8 more
doaj   +1 more source

Won't you come to me in Canada? [music] /

, 1908
For voice and piano.; Cover title.; "By special arrangement with Francis, Day & Hunter ...".; "Sung by Miss Irene Beaumont".; "Mullen's popular 6d edition".; Also available online http://nla.gov.au/nla.mus-vn1912439; Library's N and NL copies lack ...
Neat, John.
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source