Results 121 to 130 of about 9,315,628 (295)

Il ruolo del design nella progettazione alberghiera

, 2014
l'autore è stato invitato a stendere un contributo sul ruolo del design nell'ambito della progettazione alberghiera, evidenziando le varie declinazioni della disciplina- design strategico, design dei servizi, design della comunicazione, interior design,
SCULLICA, FRANCESCO, dipartimento di design   +1 more
core  

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Experimental and prediction analysis of high-velocity impact resistance of 3D printed PLA and carbon fiber reinforced PLA composites

Materials Research Express
This work describes the high-velocity impact behaviour of 3D-printed square plates manufactured from neat PLA and carbon fiber-reinforced PLA (CFPLA) composites.
Yogeshwaran Velmurugan, Chandradass Jeyaseelan   +1 more
doaj   +1 more source

Deliverable D1.1 - NEAT Architecture [Elektronisk resurs]

, 2016
Ossification of the Internet transport-layer architecture is a significant barrier to innovation of the Internet. Such innovation is desirable for many reasons.
Welzl, Michael,, Fairhurst, Gorry,, Evensen, Kristian Riktor,, Damjanovic, Dragana,, Papastergiou, Giorgos,, Bozakov, Zdravko,, Ros, David,, Fosselie Hansen, Audun,, Brunström, Anna,, Eckert, Toerless,, McManus, Patrick,, Mangiante, Simon,, Tüxen, Michael,, Vyncke, Eric,, Jones, Tom,, Grinnemo, Karl-Johan,, Khademi, Naeem,   +16 more
core  

A NEAT framework for application-awareness in SDN environments

, 2017
Software-Defined Networking (SDN) has led to a paradigm shift in the way how networks are managed and operated. In SDN environments the data plane forwarding rules are managed by logically centralized controllers operating on global view of the network ...
Mangiante, Simone,, Bozakov, Zdravko, Kassler, Andreas, Santos, Ricardo,, Santos, Ricardo, Bozakov, Zdravko,, Anna Brunstrom, Brunström, Anna,, Mangiante, Simone, Kassler, Andreas,, Zdravko Bozakov, Ricardo Santos, Simone Mangiante, Brunström, Anna, Andreas Kassler   +14 more
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Performance characterization and combination design optimization of fast-melting SBS/CR modified asphalt

Case Studies in Construction Materials
To broaden the application prospects of fast-melting styrene-butadiene-styrene modifiers (F-SBS) and meet diverse requirements, this study utilizes crumb rubber (CR) as a partial substitute for F-SBS to prepare fast-melting SBS/CR modified asphalt (F ...
Jinyao Li, Wenwu Zhang, Weiwei Lu, Songtao Lv, Haihui Duan, Jinping Wang   +5 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Constructing the future of design : How design professionals perceive their changing role

, 2018
Design and design thinking have boomed in the past decade, expanding design considerations into new areas of application and a wide range of organizations across industry types.
Björklund, Tua A., Maula, Hanna, Akkola, Matilda   +2 more
core