Results 51 to 60 of about 31,593 (286)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Breaking the Binary: Exploring Orality in India through Typography, Cryptography and Craft [PDF]

, 2022
This thesis explores the fluidity of language through the fusion of heterogenous visual traditions — creating hybrid forms and coded communication. It voyages through the linguistic landscape of India.

core  

Optical amplification and stability of spiroquaterphenyl compounds and blends [PDF]

Journal of the European Optical Society-Rapid Publications, 2015
In this contribution, we present a systematic investigation on a series of spiroquaterphenyl compounds optimised for solid state lasing in the near ultraviolet (UV).
Fuhrmann-Lieker T., Lambrecht J., Hoinka N., Kiurski M., Wiske A., Hagelstein G., Yurttagü N., Abdel-Awwad M., Wilke H., Messow F., Hillmer H., Salbeck J.   +11 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The national emergency access target (NEAT) and the 4-hour rule: time to review the target

, 2016
Objective: We explored the relationship between the National Emergency Access Target (NEAT) compliance rate, defined as the proportion of patients admitted or discharged from emergency departments (EDs) within 4 hours of presentation, and the risk ...
Khanna, Sankalp, Boyle, Justin, Griffin, Bronwyn R., Lind, J, Cattell, R, Scott, IA, Staib, Andrew, Boyle, J, Sullivan, Clair, Cattell, Rohan, Khanna, S, Griffin, BR, Lind, James, Bell, A, Good, NM, Heiniger, L, Bell, Anthony Jr., Sullivan, C, Staib, A, Good, Norm M., Scott, Ian A., Heiniger, Liam   +21 more
core   +1 more source

Indicator-based assessment of marine biological diversity – lessons from 10 case studies across the European Seas

Frontiers in Marine Science, 2016
The Marine Strategy Framework Directive requires the environmental status of European marine waters to be assessed using biodiversity as one out of 11 descriptors, but the complexity of marine biodiversity and its large span across latitudinal and ...
Laura Uusitalo, Hugues Blanchet, Hugues Blanchet, Jesper H. Andersen, Olivier Beauchard, Torsten Berg, Silvia Bianchelli, Annalucia Cantafaro, Jacob Carstensen, Laura Carugati, Sabine Cochrane, Sabine Cochrane, Roberto Danovaro, Roberto Danovaro, Anna-Stiina Heiskanen, Ville Karvinen, Snejana Moncheva, Ciarán Murray, Ciarán Murray, João M. Neto, Henrik Nygård, MARIA PANTAZI, Nadia Papadopoulou, Nomiki Simboura, Greta Srėbalienė, Maria C Uyarra, Angel Borja   +26 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source