Results 71 to 80 of about 9,315,628 (295)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
, 2022 Purpose: Underpinned by the fit-fluency framework, this research aims to explore the effect of visual entropy (i.e. the neatness or disorder of food presentation) on the likelihood to purchase under different time-related positioning conditions.
Thaichon, Park +5 more
core +1 more source
Open-Source Philosophy in Fashion Design: Contesting Authorship Conventions and Professionalism [PDF]
, 2020 This paper investigates open-source fashion approach as a design philosophy and a phenomenon that demonstrates an alternative to the concept of authorship of fashion designers.
Annamari Vänskä +3 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Design Education as a Catalyst for Change
, 2018 Designers play a role in shaping our world, both literally and figuratively. Human lives are spent interacting with designed artefacts, systems, and processes.
Mulder, Ingrid +9 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Results in EngineeringTo address the issues of significant performance variability and insufficient theoretical support in the mix design of fully recycled aggregate concrete (FRAC) caused by the high porosity and strong water absorption of recycled aggregates, this study ...
Xianjiang Zhang +3 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Implementation of the NEAT Policy Manager [Elektronisk resurs]
, 2019 The NEAT system was developed in 2017 to increase flexibility in the choice of network transport protocol being used. One of the most important components of the NEAT system is the Policy Manager (PM), which determines what protocol is to be utilized by ...
Tobias, Sjöholm, +2 more
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