Results 71 to 80 of about 9,713,248 (288)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Long-term tensile creep behavior and stochastic Larson–Miller life prediction of commercial ABS and HIPS grades for household appliance applications

open access: yesPolymer Testing
The long-term reliability of styrenic polymers used in household appliances cannot be reliably assessed by mean rupture life alone, as deformation behavior and lifetime distribution may vary simultaneously under different applied stress–temperature ...
Jeongmu Lee   +4 more
doaj   +1 more source

Chained NEAT implementation for better adapting neural networks applied to Super Mario World

open access: yes, 2021
Con uso de redes neuronales encadenadas basadas en NEAT se crea un prototipo de un agente, juega el videojuego "Super Mario World" con posibilidad de adaptarse a varios niveles.Using chained neural networks based on NEAT, we developed a prototype capable
Kavanagh, Tomas
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A Comparison of Kernel Equating Methods Based on Neat Design

open access: yesEurasian Journal of Educational Research, 2019
Problem Durumu: Esitleme benzer icerik ve gucluk duzeyinde gelistirilen test formlari arasindaki farkliliklari duzenleyerek, bu formlardan elde edilen puanlarin birbiri yerine kullanilmasini saglayan istatistiksel bir surec olarak tanimlanabilir (Kolen, 1988).
openaire   +2 more sources

The End is Neat

open access: yes, 2005
Cover for The End is Neat, from the RISD Library Zine Collection.https://digitalcommons.risd.edu/specialcollections_zinecollection/1665/thumbnail ...
McCardle, Michael   +2 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Analysis and optimization of low-cost compression molding process for manufacture of particulate bone powder PLA composites

open access: yesDiscover Materials
Poly Lactic Acid (PLA) is a bio-based polymer gaining attracted for the fabrication of composite materials. This research examines the mechanical characteristics of biodegradable PLA composites reinforced with animal bone particles through the ...
Santha Rao Dakarapu   +5 more
doaj   +1 more source

Indicator-based assessment of marine biological diversity – lessons from 10 case studies across the European Seas

open access: yesFrontiers in Marine Science, 2016
The Marine Strategy Framework Directive requires the environmental status of European marine waters to be assessed using biodiversity as one out of 11 descriptors, but the complexity of marine biodiversity and its large span across latitudinal and ...
Laura Uusitalo   +26 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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