Results 81 to 90 of about 31,593 (286)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Deliverable D2.3 - Final Version of Core Transport System [Elektronisk resurs]

, 2017
This document presents the core transport system in NEAT, as used for development of the reference implementation of the NEAT System. The document describes the components necessary to realise the basic Transport Services provided by the NEAT User API ...
Fischer, Andreas,, Welzl, Michael,, Mangiante, Simone,, Fairhurst, Gorry,, Damjanovic, Dragana,, Rüngeler, Irene,, Weinrank, Felix,, Dale, Øystein,, Riktor Evensen, Kristian,, Bozakov, Zdravko,, Ros, David,, Brunström, Anna,, Petlund, Andreas,, Stenberg, Daniel,, Tüxen, Michael,, Jones, Tom,, Grinnemo, Karl-Johan,, Khademi, Naeem,   +17 more
core  

Fine-tuning CO2 separation of mixed matrix membranes by constructing efficient transport pathways through the addition of hybrid porous 2D nanosheets

Chemical Engineering Journal Advances
In this research, the effect of adding PEG 400 and synthesized rGONiO hybrid nanocomposite to Pebax® to design the Pebax® 1657/PEG 400/rGONiO ternary mixed matrix membrane (MMM) for CO2/CH4 and CO2/N2 separation, has been evaluated.
Adel Hosseinkhani, Mohammadreza Omidkhah, Abtin Ebadi Amooghin   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Taguchi analysis of shrinkage and warpage of injection-moulded polypropylene/multiwall carbon nanotubes nanocomposites

eXPRESS Polymer Letters, 2009
This paper focuses on the effect of multi-walled carbon nanotube (MWNT) addition on shrinkage and warpage properties of polypropylene (PP) injection mouldings before and after annealing.
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Deliverable D2.1 - First Version of Low-Level Core Transport System [Elektronisk resurs]

, 2016
This document presents the first version of the low-level Core Transport System in NEAT, to be used for development of a reference implementation of the NEAT System. The design of this core transport system takes into consideration the Transport Services
Welzl, Michael,, Mangiante, Simone,, Fairhurst, Gorry,, Damjanovic, Dragana,, Tüxen, Michael,, Papastergiou, Giorgos,, Riktor Evensen, Kristian,, Bozakov, Zdravko,, Jones, Tom,, Ros, David,, Brunström, Anna,, Grinnemo, Karl-Johan,   +11 more
core  

Surface neatness as an index of aesthetic value of everyday objects

Frontiers in Psychology
IntroductionSurface neatness is a fundamental yet underexplored determinant of the aesthetic evaluation of everyday objects. While prior research has typically examined individual surface features - such as gloss, shine, dirt, or scratches - in isolation,
Tatiana Ledneva, Andriy Myachykov, Andriy Myachykov, Yury Shtyrov, Yury Shtyrov   +4 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Adding support for NEAT to iperf3

, 2018
NEAT is an ongoing project which aims to re-enable the evolution ofthe transport layer of the Internet while at the same time providing aneasy to use API for developers of networked software.
Dahlgren, Kim, Rabitsch, Alexander, Ahmadi, Fatemeh, Karlsson Solaiman, Ari   +3 more
core