Results 151 to 160 of about 136,536 (261)

Deubiquitination of Vangl by USP6 and USP32 Regulates Planar Cell Polarity Signaling

open access: yesAdvanced Science, EarlyView.
Compartment‐specific deubiquitination controls Vangl dosage and planar cell polarity signaling. USP6 and USP32 regulate distinct subcellular pools of Vangl by removing distinct ubiquitin modifications from Vangl proteins. This regulatory mechanism safeguards PCP‐dependent embryonic morphogenesis, while aberrant USP32‐dependent stabilization of VANGL ...
Fangzi Zha   +13 more
wiley   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

open access: yesAdvanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen   +11 more
wiley   +1 more source

Are pulmonary neuroepithelial bodies sensors for acute airway hypoxia implicated in the central regulation of breathing? [PDF]

open access: yesPLoS One
Brouns I   +7 more
europepmc   +1 more source

Dan Brand, Lincoln, Neb.

open access: yes, 1960
Photograph used for a story in the Oklahoma Times newspaper. Caption: "Dan Brand, Lincoln, Neb. (2nd NAAU 1960): Dark horse of the year, booming up from ranks of also-ran tutelage of Bill Smith, last U. S. Olympic champion (1952)
King, Cliff
core  

Crystallized Domain Walls in HfO2 Enable Chessboard‐Type Ultra‐High‐Dense Ferroelectric Memory

open access: yesAdvanced Science, EarlyView.
In general, DWs in ferroelectrics stabilize within a widely spread transition region between two oppositely polarized domains, which severely limits the achievable memory density. Here, the reported DWs in HfO2 constitute perfect crystalline structures along arbitrary crystallographic directions, enabling the formation of the narrowest square‐shaped ...
Pawan Kumar   +4 more
wiley   +1 more source

DeBoer v. Neb. DMV

open access: yes, 2007
Docket Number: 07-087416 Neb. App. 760For access to these documents, please log in or contact the reference staff by emailing lawref@creighton.edu or by calling 402-280-5541 for help locating the desired ...

core  

Phase Separation of SF3B1 Serves as a Critical Post‐Transcriptional Regulator During Early Mouse Embryogenesis

open access: yesAdvanced Science, EarlyView.
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao   +15 more
wiley   +1 more source

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