Spontaneous resolution of idiopathic aortitis and pitfalls in diagnosis
Idiopathic aortitis is an inflammatory disease of the aorta that is diagnosed after the less frequent infectious and rheumatologic variants are excluded.
Yue Gao, MD +3 more
doaj +1 more source
Samskapingsprosessen i pilotprosjektet NEB-STAR [PDF]
Samskaping kan anses å være selve nøkkelen til å løse såkalte “wicked problems”, som for eksempel klimautfordringer. Dette omhandler komplekse problemer som en aktør ikke kan løse alene, men som kan løses gjennom et samarbeid mellom offentlige- og ...
Gundersen, Sara Rott +1 more
core
Independent Plastic Surgery Match Regional Trends Comparing In-person and Virtual Interview Cycles
Background:. There is a trend toward matching in a different region than previous training for the independent plastic surgery match cycles from 2019 to 2021, which differs from the trend to match within the same region for integrated plastic surgery ...
Sarah A. Mullen, BS +4 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Fast skeletal muscle troponin activation increases force of mouse fast skeletal muscle and ameliorates weakness due to nebulin-deficiency. [PDF]
The effect of the fast skeletal muscle troponin activator, CK-2066260, on calcium-induced force development was studied in skinned fast skeletal muscle fibers from wildtype (WT) and nebulin deficient (NEB KO) mice.
Eun-Jeong Lee +7 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Influence of Joint Strengthening on the Seismic Performance of Non-Engineered Buildings
Non-engineered buildings (NEBs) are prone to earthquake damage. One type of damage that often occurs in NEBs is the separation of beam and column elements owing to joint failures.
Edy Purwanto +3 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Increased medial olivocochlear reflex strength in normal-hearing, noise-exposed humans.
Research suggests that college-aged adults are vulnerable to tinnitus and hearing loss due to exposure to traumatic levels of noise on a regular basis.
Ishan Bhatt
doaj +1 more source
Influência dos Distúrbios Tropicais na Formação de Fenômenos Adversos de Atmosfera Estável no Nordeste Brasileiro [PDF]
Resumo Este estudo tem como principal objetivo avaliar a influência dos Distúrbios Tropicais (DT) do Hemisfério Norte (HN), associados com Ciclones Tropicais (CT), nos fenômenos de atmosfera estável no Nordeste do Brasil (NEB), de 2013 a 2015, a fim de ...
Lucas Carvalho Vieira Cavalcante +2 more
doaj +1 more source

