Results 61 to 70 of about 14,058 (258)

Implementation of guideline‐recommended medical therapy for patients with heart failure in Europe

ESC Heart Failure, Volume 12, Issue 2, Page 790-798, April 2025.
Abstract Physicians' adherence to guideline‐recommended heart failure (HF) treatment remains suboptimal, especially regarding the target doses. In particular, there is evidence that non‐cardiologists are less compliant with HF guideline recommendations. This is likely to have a detrimental impact on patients' survival, readmissions and quality of life.
Maurizio Volterrani, Petar Seferovic, Gianluigi Savarese, Ilaria Spoletini, Egidio Imbalzano, Antoni Bayes‐Genis, Ewa Jankowska, Michele Senni, Marco Metra, Ovidiu Chioncel, Andrew J. S. Coats, Giuseppe M. C. Rosano   +11 more
wiley   +1 more source

Nebivolol, an antihypertensive agent, has new application in inhibiting melanoma

Anti-Cancer Drugs
Repurposing existing drugs for cancer therapy has become an important strategy because of its advantages, such as cost reduction, effect and safety. The present study was designed to investigate the antimelanoma effect and possible mechanisms of action ...
Shuping Yang, Zhi Li, Ji Yi, Mingyue Pan, Weiling Cao, Jing Ma, Peng Zhang   +6 more
semanticscholar   +1 more source

Adrenergic Blockade by Nebivolol to Suppress Oral Squamous Cell Carcinoma Growth via Endoplasmic Reticulum Stress and Mitochondria Dysfunction

Frontiers in Pharmacology, 2021
Adrenergic nerve fibers in the tumor microenvironment promote tumor growth and represent a potential target for cancer therapy. However, the effectiveness of targeting adrenergic nerve fibers for oral squamous cell carcinoma (OSCC) therapy needs to be ...
Qian Chen, Han Jiang, Zhen Wang, Luyao Cai, Yu-Chen Jiang, Liang Xie, Yu Zhou, Xin Zeng, N. Ji, Yingqiang Shen, Qian Chen   +10 more
semanticscholar   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

Acta Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen, Jari Haukka, Tuomas Lilius, Sirpa Loukovaara   +3 more
wiley   +1 more source

Comparison of tablet splitting techniques for dosing accuracy of nebivolol tablets: Hand splitting versus tablet cutter and knife

Saudi Pharmaceutical Journal, 2021
Tablet splitting is a common practice in clinical settings to lower doses, facilitate swallowing or save costs. Splitting devices can be used when hand splitting is difficult or painful.
Seval Olgac, Duygu Yılmaz Usta, T. Incecayir   +2 more
semanticscholar   +1 more source

Effect of Nebivolol and Olmesartan on 24-Hour Brachial and Aortic Blood Pressure in the Acute Stage of Ischemic Stroke

International Journal of Hypertension, 2019
Background. Elevated blood pressure (BP) in the acute phase of ischemic stroke is associated with heightened risk of early disability and death. However, whether BP-lowering in this setting is beneficial and the exact levels at which BP should be ...
Eleni Georgianou, Panagiotis I. Georgianos, Konstantinos Petidis, Konstantinos Markakis, Ioanna Zografou, Asterios Karagiannis   +5 more
doaj   +1 more source

Therapeutic potential of small molecules that block receptor‐induced Kv7/M‐current suppression in neuroprotection, seizures, and pain

British Journal of Pharmacology, EarlyView.
Receptor‐induced Kv7/M‐current suppression increases neuronal activity and contributes to pathology of several conditions. A new class of Kv7 modulators identified in this study attenuates M‐current suppression and shows therapeutic effects. Abstract Background and Purpose Neuronal Kv7 channels generate low voltage–gated potassium currents known as the
Young Woo Kim, Pavan Kumar Behara, Lamees Alhassen, Cindy Wong, Olivier Civelli, Naoto Hoshi   +5 more
wiley   +1 more source

Nebivolol-induced hepatoxicity: a case report

European Journal of Case Reports in Internal Medicine
Nebivolol is a third-generation beta-blocker known for its high selectivity for beta-1 adrenergic receptors and its unique ability to induce vasodilation via nitric oxide (NO) release.
Lynn Srour, Majed Ali, Karam Karam, Elias Fiani   +3 more
doaj   +1 more source

Efectos de la administración crónica de carvedilol sobre la variabilidad de la presión arterial y el daño de órgano blanco en ratas con desnervación sinoaórtica [PDF]

, 2015
Background: Increased blood pressure variability is a novel risk factor for the development of target organ injury both in hypertensive and normotensive subjects, so its reduction should be considered as a new therapeutic goal. Objective: The aim of this
Bertera, Facundo Martin, Carranza, Maria Andrea, del Mauro, Julieta Sofía, Donato, Pablo Martín, Gelpi, Ricardo Jorge, Gorzalczany, Susana Beatriz, Höcht, Christian, Santander Plantamura, Yanina Alejandra, Taira, Carlos Alberto   +8 more
core  

The Effect of Low-Dose Carvedilol, Nebivolol, and Metoprolol on Central Arterial Pressure and Its Determinants: A Randomized Clinical Trial [PDF]

, 2013
In this prospective, open-label, randomized, controlled clinical trial the effects of low-dose carvedilol, nebivolol, and metoprolol on central arterial pressure and augmentation index (AIx) and its heart rate-corrected value (AIx@75) were assessed.
Agabiti-Rosei, Barna, Davis, Dhakam, El, Goldberger, Jabbour, Kampus, Laurent, Liao, London, Mackenzie, Mahmud, Morgan, Murgo, Nishiyama, Salvi, Shah, Takazawa, Tham, Westerhof, Wilkinson, Williams, Xiaozhen, Zepeda   +24 more
core   +1 more source