Results 51 to 60 of about 5,721 (196)
Aim.Compare the effects of bisoprolol, nebivolol and sotalol on the functional state of patients with ventricular arrhythmias (VA). Material and methods.120 patients with VA against the background of essential hypertension or its combination with ...
Iosif Z. Shubitidze, Vitalii G. Tregubov
doaj +1 more source
Estrogen modulates β‐AR signaling in a context‐dependent manner influenced by species, sex, age, tissue, and vascular health, highlighting challenges in translating findings from experimental models to human cardiovascular physiology. ABSTRACT Cardiovascular diseases remain the leading global cause of morbidity and mortality, with notable sex‐specific ...
Basant Elsaid +5 more
wiley +1 more source
Pharmacological properties of nebivolol
Nebivolol is a third generation β1 selective beta-blocker with vasodilatory properties which is approved for the treatment of hypertension and heart failure. The vasodilatory effect is nitric-oxide mediated and activated via β3-agonism. Nebivolol has the
Komsuoğlu Çelikyurt, Feride İpek
core +1 more source
Nebivolol: Endothelium-Mediated Vasodilating Effect
Nebivolol, a racemic mixture of (S,R,R,R) and (R,S,S,S) enantiomers, is the most beta (1)-selective adrenoceptor antagonist currently available for clinical use.
James M. Ritter, Ritter, J M
core +1 more source
Nebivolol other beta blockers in patients with hypertension and erectile dysfunction
Erectile dysfunction (ED) impacts over 100 million men worldwide and occurs at a higher incidence in men with hypertension. Beta blockers are one of several antihypertensive drug classes associated with ED.
Randall P. Sharp, Barry J. Gales
doaj +1 more source
Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang +4 more
wiley +1 more source
Aim. This subanalysis of the Study of the Effects of Nebivolol Intervention on Outcomes and Hospitalisation in Seniors with Heart Failure (SENIORS) investigates whether treatment with nebivolol, a β-blocker with nitric oxide-releasing properties, can ...
G. Ambrosio +10 more
doaj +1 more source
A chemoenzymatic synthesis of (1R,2S)‐metaraminol was developed by combining gold(I)‐catalysed alkyne hydration and stereoselective biotransamination in a sequential one‐pot process. Various phenol protection strategies were considered in oxidation‐reduction sequences, providing access to enantiopure propargylic alcohols as starting materials for ...
Lorena Escot +2 more
wiley +1 more source
The first enantioselective total synthesis of the antihypertensive agent (S,R,R,R)-nebivolol (3) is described. The synthesis includes the efficient (EBTHI)Zr-catalyzed kinetic resolutions of cycloheptenyl styrenyl ethers 8 and 16, which are subsequently ...
Charles W. Johannes (1617154) +3 more
core +2 more sources
Effect of nebivolol on liver regeneration in an experimental 70% partial hepatectomy model
Background: Factors affecting liver regeneration are still relevant. The purpose of this study is to investigate the effect of nebivolol treatment on liver regeneration in rats in which 70% partial hepatectomy was performed.
Fatih Sumer +6 more
doaj +1 more source

