Novel perspectives in redox biology and pathophysiology of failing myocytes: modulation of the intramyocardial redox milieu for therapeutic interventions - A review article from the Working Group of Cardiac Cell Biology, Italian Society of Cardiology [PDF]
The prevalence of heart failure (HF) is still increasing worldwide, with enormous human, social, and economic costs, in spite of huge efforts in understanding pathogeneticmechanisms and in developing effective therapies that have transformed this ...
Angelini, Annalisa +8 more
core +5 more sources
The present investigation aimed to prepare a self micro emulsifying drug delivery system (SMEDDS) for the dissolution enhancement of nebivolol hydrochloride.
R. Sura, S. Cvs, S. S. Rachamalla
semanticscholar +1 more source
Purpose: To investigate whether fluvoxamine coadministration can influence the pharmacokinetic properties of nebivolol and its active hydroxylated metabolite (4-OH-nebivolol) and to assess the consequences of this potential pharmacokinetic interaction ...
Ana-Maria Gheldiu +10 more
doaj +1 more source
In vivo Study of the Effect of 5 and 10% Nebivolol Cream on Hair Growth in Mice Models
Background: Hair growth promotion via the use of vasodilators represents an important approach in hair loss management as they have proven to be effective in promoting hair growth.
A. R, A. Raghif, Z. A. Mahdi
semanticscholar +1 more source
Effects of Metoprolol and Nebivolol on Exercise Blood Pressure in Patients with Mild Hypertension
Objectives. We planned to compare the impact of two beta blockers, metoprolol and nebivolol, on arterial blood pressure during exercise in patients with mild hypertension. Methods.
Huseyin Ugur Yazici +3 more
doaj +1 more source
Introduction Overactive bladder (OAB) is a disease that significantly decreases quality of life. Adverse effects of the drugs currently used in OAB treatment limit their use in patients with hypertension. Nebivolol (a β 1 -adrenergic receptor blocker) is
Andrzej F. Wróbel +4 more
doaj +1 more source
Protective effect of nebivolol on rat ovary exposed to deltamethrin toxicity [PDF]
Purpose: We aimed to investigate the antioxidant activity of nebivolol against possible damage to the ovarian tissue due to the application of deltamethrin as a toxic agent, by evaluating histopathological proliferating cell nuclear antigen (PCNA) and ...
Serap Otçu +4 more
doaj +1 more source
Comparing the Molecular Pharmacological Properties of Existing β-Blockers to Determine the Theoretically Most "Ideal" Anti-Cancer β-Blocker. [PDF]
ABSTRACT There is increasing evidence, from cellular, animal and human epidemiological studies, linking β‐blockers with reductions in cancer growth and metastasis. Propranolol is the most investigated β‐blocker for cancer; although as many different off‐patent β‐blockers exist, there is little commercial incentive to drive comparative clinical trials ...
Baker JG.
europepmc +2 more sources
Tempol-nebivolol therapy potentiates hypotensive effect increasing NO bioavailability and signaling pathway [PDF]
Nebivolol is a third generation beta blocker with endothelial nitric oxide synthase (eNOS) agonist properties. Considering the role of reactive oxygen species (ROS) in the uncoupling of eNOS, we hypothesized that the preadministration of an antioxidant ...
Balestrasse, Karina Beatriz +6 more
core +1 more source
Nebivolol-induced gynecomastia
Adverse drug reactions play a substantial role in the etiology of gynecomastia. Gynecomastia as an adverse drug reaction, related to some cardiovascular drugs, has been reported in literature. Nebivolol is a third generation beta-blocker, and gynecomastia as an adverse effect on the consumption of this drug has not been reported in any article yet.
Köklü, Erkan +4 more
openaire +3 more sources

