Results 31 to 40 of about 14,058 (258)

Novel perspectives in redox biology and pathophysiology of failing myocytes: modulation of the intramyocardial redox milieu for therapeutic interventions - A review article from the Working Group of Cardiac Cell Biology, Italian Society of Cardiology [PDF]

open access: yes, 2016
The prevalence of heart failure (HF) is still increasing worldwide, with enormous human, social, and economic costs, in spite of huge efforts in understanding pathogeneticmechanisms and in developing effective therapies that have transformed this ...
Angelini, Annalisa   +8 more
core   +5 more sources

Development and Evaluation of Self Micro Emulsifying Drug Delivery System (SMEDDS) for Nebivolol Hydrochloride

open access: yesInternational Journal of Life Science and Pharma Research, 2022
The  present  investigation  aimed  to  prepare  a  self  micro  emulsifying  drug  delivery  system  (SMEDDS)  for  the dissolution enhancement of nebivolol hydrochloride.
R. Sura, S. Cvs, S. S. Rachamalla
semanticscholar   +1 more source

Investigation of a Potential Pharmacokinetic Interaction Between Nebivolol and Fluvoxamine in Healthy Volunteers

open access: yesJournal of Pharmacy & Pharmaceutical Sciences, 2017
Purpose: To investigate whether fluvoxamine coadministration can influence the pharmacokinetic properties of nebivolol and its active hydroxylated metabolite (4-OH-nebivolol) and to assess the consequences of this potential pharmacokinetic interaction ...
Ana-Maria Gheldiu   +10 more
doaj   +1 more source

In vivo Study of the Effect of 5 and 10% Nebivolol Cream on Hair Growth in Mice Models

open access: yesInternational Journal of Drug Delivery Technology, 2022
Background: Hair growth promotion via the use of vasodilators represents an important approach in hair loss management as they have proven to be effective in promoting hair growth.
A. R, A. Raghif, Z. A. Mahdi
semanticscholar   +1 more source

Effects of Metoprolol and Nebivolol on Exercise Blood Pressure in Patients with Mild Hypertension

open access: yesThe Scientific World Journal, 2013
Objectives. We planned to compare the impact of two beta blockers, metoprolol and nebivolol, on arterial blood pressure during exercise in patients with mild hypertension. Methods.
Huseyin Ugur Yazici   +3 more
doaj   +1 more source

The efficacy of nebivolol on spontaneously hypertensive rats with overactive bladder – an experimental study

open access: yesArchives of Medical Science, 2019
Introduction Overactive bladder (OAB) is a disease that significantly decreases quality of life. Adverse effects of the drugs currently used in OAB treatment limit their use in patients with hypertension. Nebivolol (a β 1 -adrenergic receptor blocker) is
Andrzej F. Wróbel   +4 more
doaj   +1 more source

Protective effect of nebivolol on rat ovary exposed to deltamethrin toxicity [PDF]

open access: yesActa Cirúrgica Brasileira, 2023
Purpose: We aimed to investigate the antioxidant activity of nebivolol against possible damage to the ovarian tissue due to the application of deltamethrin as a toxic agent, by evaluating histopathological proliferating cell nuclear antigen (PCNA) and ...
Serap Otçu   +4 more
doaj   +1 more source

Comparing the Molecular Pharmacological Properties of Existing β-Blockers to Determine the Theoretically Most "Ideal" Anti-Cancer β-Blocker. [PDF]

open access: yesPharmacol Res Perspect
ABSTRACT There is increasing evidence, from cellular, animal and human epidemiological studies, linking β‐blockers with reductions in cancer growth and metastasis. Propranolol is the most investigated β‐blocker for cancer; although as many different off‐patent β‐blockers exist, there is little commercial incentive to drive comparative clinical trials ...
Baker JG.
europepmc   +2 more sources

Tempol-nebivolol therapy potentiates hypotensive effect increasing NO bioavailability and signaling pathway [PDF]

open access: yes, 2013
Nebivolol is a third generation beta blocker with endothelial nitric oxide synthase (eNOS) agonist properties. Considering the role of reactive oxygen species (ROS) in the uncoupling of eNOS, we hypothesized that the preadministration of an antioxidant ...
Balestrasse, Karina Beatriz   +6 more
core   +1 more source

Nebivolol-induced gynecomastia

open access: yesJournal of Pharmacology and Pharmacotherapeutics, 2015
Adverse drug reactions play a substantial role in the etiology of gynecomastia. Gynecomastia as an adverse drug reaction, related to some cardiovascular drugs, has been reported in literature. Nebivolol is a third generation beta-blocker, and gynecomastia as an adverse effect on the consumption of this drug has not been reported in any article yet.
Köklü, Erkan   +4 more
openaire   +3 more sources

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